摘要
目的了解急性胰腺炎住院患者人口学分布、亚型和合并疾病特征以及用药规律。方法采集全国19家三级甲等综合医院信息系统（HIS）中第一诊断为胰腺炎（包括急性胰腺炎、急性胆汁性胰腺炎、胰腺炎3个亚型）的住院患者信息,采用频数统计方法分析患者人口学特征、出入院情况、合并疾病及用药信息。结果共纳入5433例急性胰腺炎患者,其中男性2994例,女性2048例,记录缺失391例;年龄多集中于18～65岁共1789例;有中医证型记载173例,主要以肝胆湿热型为主。治疗结果中急性胰腺炎治愈2038例,好转1396例;急性胆汁性胰腺炎治愈221例,好转56例;胰腺炎治愈150例,好转139例。最常见的合并症为胆结石、胆道感染、消化系统肿瘤、高血压病、脂肪肝。在治疗使用338种西药和224种中成药中,西药生长抑素最多为3526例,中药最多为复方甘草酸1187例。住院天数以8～14天最多共1 888例,住院花费以10 000～20 000元最多共1 315例。结论急性胰腺炎患者主要为男性青壮年人群,常有胆结石或胆道感染等并发症,中医证候以肝胆湿热为主,平均住院时间多在8～28天,中西医结合治疗方法在急性胰腺炎的临床治疗中非常普遍。
Objective To research the demographic distribution,subtypes and concurrent disease characteristics of hospitalized patients with acute pancreatitis（ AP） and analyze the drug rules. Methods The information of hospitalized patients with pancreatitis including three subtypes such as AP,acute biliary pancreatitis and pancreatitis was collected in the hospital information system（ HIS） of 19 top-level hospitals nationwide. The demographic characteristics,discharged situation,hospitalization,complications and medication information were analyzed by frequency statistics. Results There were 2 994 cases of male,2 048 cases of female and 391 cases of missing records in 5 433 cases of AP. The ages of most patients（ 1 789 cases） were from 18 to 65 years old. There were 173 patients with records of TCM syndromes. The common syndrome was liver-gallbladder damp-heat syndrome. A total of 2 038 AP patients were cured and 1 396 patients were improved. A total of 221 acute biliary pancreatitis patients were cured and56 patients were improved. A total of 150 pancreatitis patients were cured and 139 patients were improved. The common complications were gallstones,biliary tract infections,digestive cancer,hypertension and fatty liver. There were338 kinds of western medicine and 224 kinds of Chinese medicine used. The commonly used western medicine was somatostatin（ used in 3 526 cases） and the commonly used Chinese medicine was compound glycyrrhizin（ used in 1 187cases）. The common hospitalization duration was 8 to 14 days（ in 1 888 cases）. The common hospitalization cost was more than 10 000 yuan and equal to or less than 20 000 yuan（ in 1 315 cases）. Conclusion Most AP patients are young males and commonly complicated by gallstones or biliary tract infections. The common TCM syndrome is livergallbladder damp-heat syndrome. The average hospitalization duration is 8 to 28 days. The common hospitalization cost is 5 000 to 100 000 yuan. The common treatment of AP is integrative medicine.
出处
《中医杂志》
CSCD
北大核心
2014年第19期1688-1691,共4页
Journal of Traditional Chinese Medicine
基金
国家重大新药创制科技重大专项资助项目(2009ZX09502-030)
关键词
急性胰腺炎
真实世界研究
肝胆湿热
医院信息系统
acute pancreatitis
real world study
liver-gallbladder damp-heat syndrome
hospital information system
作者简介
通讯作者：ktzu2014@163．com，（010）64014411转3302
