摘要
目的探讨糖链抗原125(CA125)在细菌性腹膜炎检测中的临床价值,为细菌性腹膜炎的诊断提供参考依据。方法选取医院2010年3月-2013年3月收治的50例肝硬化腹水发生细菌性腹膜炎患者作为观察组,同时选取50例肝硬化腹水无细菌性腹膜炎患者作为对照组;同时抽取两组患者静脉血和腹水,并对所采集血样进行血清及腹水CA125测定,然后进行临床对比分析。结果观察组患者血清CA125水平(136.41±57.42)U/L,对照组为(26.12±16.13)U/L,两组比较差异有统计学意义(P<0.01);观察组腹水CA125水平(187.42±53.71)U/L,对照组为(29.85±15.49)U/L,两组比较差异有统计学意义(P<0.01)。结论细菌性腹膜炎患者体内的CA125水平会大幅升高,CA125是一种可以有效诊断细菌性腹膜炎的临床指标。
OBJECTIVE To explore the clinical value of carbohydrate antigen 125 （CA125 ） in diagnosis of bacterial peritonitis so as to provide guidance for diagnosis of bacterial peritonitis .METHODS A total of 50 liver cirrhosis patients with bacterial peritonitis ,who were treated in the hospital from Mar 2010 to Mar 2013 ,were assigned as the observation group ,meanwhile ,50 liver cirrhosis patients without bacterial peritonitis were chosen as the con-trol group;the venous blood and ascites were sampled from the two groups of patients ,the CA125 was detected in the serum and ascites ,and the comparison study was conducted .RESULTS The level of CA125 in the serum was （136 .41 ± 57 .42）U/L in the observation group ,（26 .12 ± 16 .13）U/L in the control group ,and there was significant difference between the two groups （ P＆lt; 0 .01 ） .The level of CA125 in the ascites was （187 .42 ± 53 .71）U/L in the observation group ,（29 .85 ± 15 .49）U/L in the control group ,and there was significant difference between the two groups （P＆lt;0 .01） .CONCLUSION The CA125 level is elevated significantly in the pa-tients with bacterial peritonitis ,and the CA125 can be used as an effective clinical indicator for diagnosis of the bacterial peritonitis .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第18期4663-4664,4667,共3页
Chinese Journal of Nosocomiology
基金
中国高校医学期刊临床专项基金资助项目(11320103)
