摘要
目的系统评价肺炎衣原体(CP)感染对不稳定型心绞痛触发的关系,为正确选择临床治疗方案提供科学依据。方法选择2000-2012年万方数据库、CNKI数据库、Pubmed、Cochrane图书馆已经收录的国内外相关文献,并进行文献索源和手工检索,降低文献漏检,应用Stata12.0统计软件对数据进行荟萃分析。结果共检索文献135篇,符合纳入标准文献12篇,心绞痛患者共1 223例,其中不稳定心绞痛737例、稳定型心绞痛486例;各文献经异质性检验不存在明显差异;采用固定效应模型进行合并,进一步分析显示,不稳定心绞痛CP感染430例感染率58.34%,稳定型心绞痛达268例感染率55.14%,不稳定心绞痛组与稳定型心绞痛CP检出率差异无统计学意义。结论 CP感染与不稳定型心绞痛触发未见明显相关性。
OBJECTIVE To evaluate relationship between Chlamydia pneumoniae （Cp） infection and incidence of unstable angina （UA） ,and provide scientific basis for correct clinical treatment of UA .METHODS Relevant litera-tures from Jan .2000 to Dec .2012 were searched in WanFang database ,CNKI ,Pubmed ,and Cochrane Library . The source of literature and manual searches were used to reduce undetected literature .The meta-analysis was car-ried out by using the Stata12 .0 software .RESULTS A total of 135 articles were retrieved ,and 12 of them met the inclusion criteria .The case number of patients with angina was 1223 ,including 737 cases of unstable angina ,486 cases of stable angina .There was no difference in heterogeneity between all articles .According to the data consoli-dation by the fixed effect model ,the infection rate of CP in patients with unstable angina was 58 .34% ,and 55 .14% of patients with stable angina .The infection rate of CP in unstable angina group and stable angina group had no significant difference .CONCLUSION There is no relationship between CP infection and the incidence of un-stable angina .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第18期4520-4522,共3页
Chinese Journal of Nosocomiology
基金
新世纪优秀人才支持计划基金项目(KCEF-11-1074)
作者简介
杨毅宁，E—mail：yangyn5126@163．com
