摘要
目的观察在常规药物治疗基础上辅以步行运动对高血压合并2型糖尿病患者糖代谢、动态血压及生活质量的影响。方法应用计步器筛选出62例在我科门诊或住院治疗且步行运动量〈5000步／d的高血压合并2型糖尿病患者，采用随机数字表法将其分为运动组（32例）及对照组（30例）。2组患者均给予常规药物（包括缬沙坦、二甲双胍、阿卡波糖）治疗，运动组患者在此基础上每天步行10000步以上（对其运动持续时间及运动强度不作限定），对照组仍按照日常习惯生活。于人选时、干预3个月后观察2组患者空腹血糖（FPG）、糖化血红蛋白（HbAlc）、空腹胰岛素（FINS）、胰岛素抵抗指数（HOMA—IR）、胰岛素敏感性（HOMA—IS）、动态血压参数及生活质量变化情况。结果2组患者分别经3个月干预后，发现运动组患者FPG[（5．41±1．23）mmol／L]、HbAlc[（6．16±0．87）％]、FINS[（8．72±2．43）mlU／L]、HOMA—IR[（2．27±1．41）]、HOMA—IS[（0．0182±0．0034）]、动态血压参数[24h收缩压为（126±13）mmHg，24h舒张压为（72±8）mmHg，白天收缩压为（132±8）mmHg，白天舒张压为（74．4±8．3）mmHg，夜间收缩压为（123．1±8．7）mmHg，夜间舒张压为（70．5±6．1）mmHg]及生活质量评分[生理功能为（87．2±11．5）分，生理职能为（73．0±14．3）分，总体健康为（78．6±15．5）分，生命活力为（68．4±18．8）分，情感职能为（68．7±20．4）分，精神健康为（78．6±19．4）分]均较人选时及对照组明显改善（P〈0．05），其间差异均具有统计学意义（P〈0．05）。结论在常规药物治疗基础上每天步行10000步以上可进一步改善缺乏运动的轻度高血压合并2型糖尿病患者糖代谢及动态血压参数，对提高患者生活质量具有重要意义。
Objective To explore the effects of walking exercise on glycometabolism, dynamic blood pressure and the quality of life of patients with both hypertension and type 2 diabetes on the basis of conventional drug treatment. Methods Sixty-two patients with both hypertension and diabetes who could support taking walking exercise of more than 5,000 steps/d were randomly divided into a walking exercise group （32 cases） and a control group （30 cases）. Both groups were given conventional drug treatment （including valsartan, acarbose and metformin）. Those in the walking exercise group took more than 10,000 steps/d of aerobic exercise while the patients in the con- trol group were just given normal community care. This continued for a period of 3 months. Fasting plasma glucose （ FPG）, glycated hemoglobin-A1C （ HbA1 c）, fasting insulin （ FINS）, the homeostasis model of assessment for insu- lin resistence index （ HOMA-IR）, the homeostasis model of assessment for insulin sensitivity （HOMA-IS） , dynamic blood pressure parameters and quality of life were observed. Results In the walking exercise group, the FPG, HbAlc, FINS, HOMA-IR, HOMA-IS, dynamic blood pressure and quality of life indicators were all significantly dif- ferent after 3 months of daily walking exercise compared with either baseline or the control group. Conclusion Accompanied by conventional drug therapy, 10,000 steps/d of walking exercise can improve the glucose metabolism, dynamic blood pressure and quality of life of patients suffering from mild hypertension and type 2 diabetes.
出处
《中华物理医学与康复杂志》
CAS
CSCD
北大核心
2014年第8期609-613,共5页
Chinese Journal of Physical Medicine and Rehabilitation
关键词
步行运动
高血压
2型糖尿病
糖代谢
动态血压
生活质量
Walking exercise
Hypertension
Diabetes
Glucose metabolism
Blood pressure
Quality of life
作者简介
通信作者：邱春光，Email：wzbdoc@163．com
