摘要
目的探讨比索洛尔、通心络胶囊联合分时段给药治疗不完全冠状动脉心肌桥的临床疗效和患者用药依从性。方法将42例不完全冠状动脉心肌桥患者随机分为治疗组和对照组,每组21例,治疗组采取联合分时段口服比索洛尔、通心络胶囊的方法进行治疗;对照组采取美托洛尔、通心络胶囊联合口服的方法进行治疗(治疗组和对照组基础治疗方案相同),比较两组临床疗效及患者用药依从性。结果治疗组显效率为85.7%,高于对照组的57.1%,差异有统计学意义(P<0.05);治疗组与对照组总有效率比较差异无统计学意义(P>0.05);治疗组患者用药依从性为95.2%,高于对照组的71.4%,差异有统计学意义(P<0.05)。结论比索洛尔联合通心络胶囊分时段给药治疗冠状动脉不完全心肌桥较美托洛尔、通心络胶囊联合给药的治疗方法显效率高,患者用药依从性好,在临床上具有推广前景。
Objective To investigate the clinical effects and medication compliance of combined drug treatment of bisoprolol and Tongxinluo capsule at different period of time for incomplete myocardial bridge. Methods Forty-two patients with incomplete myocardial bridge were randomly divided into treatment group and control group,with 21 cases in each group. Patients in the treatment group received combined drug treatment of bisoprolol and Tongxinluo capsule,and the patients in control group received combined oral treatment of metoprolol and Tongxinluo capsule. The clinical effects and medication compliance were compared between the two groups. Results The efficiency of treatment group( 85. 7%) was significant higher than that of control group( 57. 1%). There was no significant difference in the total effective rate between treatment group and control group( P〉0. 05). The medication compliance of treatment group( 95. 2%) was significant higher than that of control group( 71. 4%).Conclusion The efficiency of the combined drug treatment of bisoprolol and Tongxinluo capsule is significant higher than that of metoprolol and Tongxinluo capsule for incomplete myocardial bridge. The medication compliance of bisoprolol and Tongxinluo capsule is good,so it has good clinical promotion prospects.
出处
《临床医学》
CAS
2014年第8期4-6,共3页
Clinical Medicine
关键词
心肌桥
冠状动脉
通心络胶囊
比索洛尔
Myocardial bridge
Coronary artery
Tongxinluo capsule
Bisoprolol