摘要
目的探讨血T-SPOT.TB用于矽肺并发结核(SCTB)的诊断价值。方法选择SCTB病例62例,根据最终诊断结果分为SCTB组和矽肺(SC)组。使用血T-SPOT.TB、结核菌素皮肤试验(TST)、抗酸杆菌(AFB)、结核抗体(TB-A)试验等4种方法对两组研究对象进行检测,并对比4种检测方法的诊断价值。结果4种方法检测SCTB的敏感度分别为94.4%、52.8%、38.9%、41.7%,其中血T-SPOT.TB检测SCTB的敏感度最高(P<0.0001)。4种方法检测SCTB的阴性预测值分别为91.7%、52.8%、48.8%、55.3%,其中血TSPOT.TB检测SCTB的阴性预测值(91.7%)最高(P<0.01)。结论血T-SPOT.TB用于SCTB的检测,具有高敏感度、高阴性预测值特点,可用于SCTB疑似病例的诊断。
Objective To explore the diagnostic value of blood T-SPOT. TB for silicosis complicated with tu-berculosis （ SCTB） . Methods 62 patients with SCTB were divided into SCTB group and SC group according to the＆amp;nbsp;results of the final diagnosis. 4 kinds of methods, blood T- SPOT. TB, tuberculin skin test （ TST） , acid fast stain （ AFB） , tuberculosis antibody test （ TB-A） were used in the two groups, and the diagnostic value of the 4 kinds of detection methods were compared. Results The sensitivity of the 4 kinds of methods was 94. 4%, 52. 8%, 38. 9%and 41. 7% respectively, and the sensitivity of blood T-SPOT. TB was the highest （all P〈0. 001）. The negative pre-dictive value was 91. 7%, 52. 8%, 48. 8% and 55. 3% respectively, and blood T-SPOT. TB was the highest （ all P〈0. 01）. Conclusion Blood T-SPOT. TB has the advantages of higher sensitivity and negative predictive value in the detection of SCTB, which can be applied to the diagnosis of suspected SCTB cases.
出处
《临床肺科杂志》
2014年第9期1641-1645,共5页
Journal of Clinical Pulmonary Medicine
作者简介
通讯作者：胡克，E—mail：huke—rmhospital@163．com
