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启动子结构和功能研究进展 被引量:21

Advances of the Studies on Structure and Function of Promoter
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摘要 转录起始是一种最重要的表达调节方式,通过多种蛋白质与启动子的配位结合起始转录,参与基因的表达调控过程。而启动子作为基因表达调控的重要顺式作用原件,在原核和真核生物中均存在。对核心启动子结构特征中多种保守顺式调控原件及基本转录因子的结构和功能进行了阐述。 Gene expression and its regulation are dependent, on to a great extent, on transciption. An elementary transciption reaction is initiated by the recognition of regulatory regions and especially promoters. Promoters is the cis-regulatory element of gene expression and its regulation, exsit in eukaryotes and prokaryotes. This paper expounded on the general characteristics and the function of promoter segment and cis-element functions.
出处 《生物技术通报》 CAS CSCD 北大核心 2014年第8期40-45,共6页 Biotechnology Bulletin
基金 国家肉牛牦牛产业技术体系建设专项资金(CARS-38)
关键词 启动子 结构 顺式作用元件 功能 转录因子 Promoter Structure cis-acting elements Function Transcription factor
作者简介 王婧,女,博士研究生,研究方向:兽医药理学与新药创制;E-mail:kenhtsjj@163.com 张继瑜,男,研究员,博士生导师,研究方向:兽用药物及其基础;E-mail:infzjy@sina.com
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