摘要
目的探讨老龄血管性痴呆(VD)患者临床与影像学特征。方法 68例老年VD患者为VD组,选择同期身体健康的65例老年体检者为参照,设为健康组,对比2组临床特征与影像资料。结果 VD组与健康组MoCA评分中除物体命名评分不具显著性差异,其余各项VD组均明显不及健康组(P<0.001);VD组MMSE与BSSD评分均明显低于对照组(P<0.001)。CT检查发现患者侧脑室、丘脑、基底节等部位均有密度较低的病灶;MRI检查显示患者额、颞与顶叶皮层下等病变区域部位出现高信号。结论老年VD患者以记忆、认知、注意力及视觉等认知功能障碍为主要特征,影像学检查有助于临床掌握患者血管与病变组织情况,为及时有效诊治与判断预后提供了依据。
Objective To study the clinical and neuroimaging characteristics of elderly patients with vascular dementi-a.Methods 68 cases of senile VD patients were selected as the research subjects ,set for VD group ,65 healthy elder for medi-cal examination were selected for reference ,as a health group. The clinical symptoms and imaging data in two groups were compared.Results There was no significant difference in the object named scores in the VD group and healthy group ,the rest scores of the VD group were significantly less than those of healthy group （P〈0.001）;BSSD and MMSE scores of VD group were significantly less than those of control group （P〈0.001）. In neuroimaging of VD group ,all patients show symptoms of brain atrophy. CT examination found lower density lesions in the area around lateral ventricle ,in thalamus and basal ganglia;MRI showed there were high signal lesions in subcortexes of frontal and temporal and parietal lobes.Conclusion The memory , attention ,cognitive and visual dysfunction in elderly patients with VD are the main symptoms ,and neural imaging examination is helpful for mastering clinical vascular lesions and pathological changes ,which can provide basis for the timely and effective treatment and judging prognosis.
出处
《中国实用神经疾病杂志》
2014年第13期19-20,共2页
Chinese Journal of Practical Nervous Diseases
