摘要
目的:观察大承气汤（DT）经胃给药对家兔胃动素分泌和胃电活动的影响。方法:用DT给家兔经胃给药,分别观察30、90、210min胃动素分泌和胃电活动结果。结果:给药后30min,胃动素分泌和胃电活动均受到明显抑制;给药后90min胃动素水平仍低于给药前,但呈上升趋势,而胃电活动已恢复至给药前水平且呈逐渐加强趋势;给药后210min胃动素水平超过给药前,胃电活动则明显增强。结论:DT经胃给药对家兔胃动素分泌和胃电活动均有先抑制后促进的作用。
Objective: To observe the effect of Dachengqitang (DT) on rabbits motilin secretion and elec-trogastroaction with dosing stomach. Method: To dose rabbits with DT and observe respectively the results of motilin secretion and electrogastroaction after 30, 90 and 210 minutes. Results; 30 min after dosing, its motilin secretion and electrogastroaction were obviously inhibited; 90 min later, the level of motilin was below that before dosing with a rising trend, and electrogastroaction restored to the level before. dosing with a strengthening trend; 210 min later, the level of motilin exceeded that before dosing while the electrogastroaction were obviously strengthened. Conclusion: DT, after being dosed to stomach, can inhibit and then accelerate rabbits motilin secretion and electrogastroaction.
出处
《河北中医药学报》
2002年第2期1-3,共3页
Journal of Hebei Traditional Chinese Medicine and Pharmacology
关键词
大承气汤
胃动素
胃电
家兔
中药
药理
Dachengqitang (DT)
motilin
gastric electricity
rabbit
