摘要
目的:探讨中医再生医学的基础理论、概念与研究内容,分析中医再生医学学科的形成与展望。方法:在前期精与干细胞系列理论研究和中医药与干细胞相互作用的实验研究基础上,提出中医再生医学的概念与内涵,分析中医再生医学学科的形成与展望。结果:中医再生医学是研究中医药调控干细胞以促进组织与器官再生、防治疾病、延缓衰老的一门科学。就是以干细胞与精相关理论为基础,通过中医药学手段,调动机体自身的潜力,通过改变干细胞的微环境,激活体内处于静止期或休眠状态的干细胞,使其增殖、迁移、分化,或以中医药手段联合干细胞移植、组织工程重建以提高效率,从而达到促进组织自我更新与修复、功能重建以防治疾病或延缓衰老的目的。中医再生医学内涵的核心是中医药调控干细胞。因此,再生医学相关的研究内容,均可在中医药理论与实践的基础上,以干细胞为靶点,来进行研究、阐释与深入挖掘。结论:本研究指明中医再生医学未来的研究内容与发展方向,为中医再生医学学科的发展奠定了基础。
The essay was written to discuss the basic theory, concept and research content of Traditional Chinese Regenerative Medicine(TCRM) and analyze the formation and future development of TCRM subject. Based on series theoretic and experimental research of stem cell and traditional Chinese medicine(TCM), we put forward new concept and connotation of TCRM and analyzed the development of this new subject. TCRM is the study of Traditional Chinese Medicine regulating stem cell to accelerate tissue and organ regeneration, prevent and treat related disease and delay ageing. TCRM, based on the theory of stem cell and essence, using the technique of TCM, is to activate the inner potential ability of body, which can change the microenvironment of stem cell, activate inner silence stem cell to proliferate, migrate and differentiate, or combine with stem cell transplantation and tissue engineering with increasing efficiency, to achieve the aim of prevention and treatment of disease and anti-aging by accelerate self-renewing, selfrepairing and functional rebuilding. The core connotation of TCRM is regulating stem cell by TCM. Therefore, targeting on stem cell, the research content of regenerative medicine can be researched, explained and deeply excavated on the base of theory and practice of TCM. Our research pointed out research content and development direction of TCRM in the future and built up a good basis for TCRM advancement.
作者
张进
Zhang Jin(The Research Center of Basic Integrative Medicine,Guangzhou University of Chinese Medicine, Guangzhou 510006,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2018年第9期1489-1495,共7页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
广东省自然科学基金委面上基金项目(2018A030313632):FNDC5/Irisin激活Wnt通路调控运动促小鼠骨稳态的作用
负责人:张进
广州中医药大学科研创新团队项目(2016KYTD10):干细胞与中医再生医学团队
负责人:张进
广州中医药大学归国留学人员"薪火计划"(XH20140108):左归丸对FNDC5基因敲除小鼠的抗衰老作用及机制研究
负责人:张进
关键词
再生医学
干细胞
中医再生医学
概念
研究内容
Regenerative medicine
stem cell
traditional Chinese regenerative medicine
concept
research content
作者简介
通讯作者:张进,博士,副教授,南开大学教育部访问学者,美国塔夫茨大学访问学者,主要研究方向:干细胞与中医再生医学。
