摘要
探讨慢性肝炎患者肝癌的患病率及其影响因素。方法将194例乙肝与丙肝患者依据临床诊断结果进行分组,其中A组为未发展为肝癌的80例乙肝患者,B组为72例乙肝相关性肝癌患者,C组为未发展为肝癌的24例丙肝患者,D组为18例丙肝相关性肝癌患者。采用统一的自行设计的调查问卷对患者进行调查。分析患者由肝炎发展为肝癌的影响因素。结果饮酒及肝癌家族史与乙肝发展为肝癌呈显著正相关(P<0.05或0.01),抗病毒治疗与其呈显著负相关(P<0.01)。饮酒与丙肝发展为肝癌呈显著正相关(P<0.05),抗病毒治疗与其呈显著负相关(P<0.05)。结论乙肝和丙肝患者应戒酒,及早并坚持开展抗病毒治疗干预,有肝癌家族史的乙肝患者应警惕肝癌发生风险,注意密切监测和随访,提高患者的生存质量。
Objective To investigate the prevalence of liver cancer in patients with chronic hepatitis and its influencing factors.Methods 194 patients with hepatitis B and hepatitis C were divided according to clinical diagnosis results.80 patients with hepatitis B who did not develop liver cancer were seen as group A,72 patients with hepatitis B related liver cancer were seen as group B,24 patients with hepatitis C who did not develop liver cancer were seen as group C,18 patients with hepatitis C related liver cancer were seen as group D.Patients were surveyed using a unified and self-designed questionnaire.Results There was a significant positive correlation between drinking,family history of liver cancer and hepatitis B developed into liver cancer (P<0.05 or 0.01),and antiviral therapy was significantly negatively correlated (P<0.01).There was a significant positive correlation between drinking and hepatitis C developed into liver cancer (P<0.05),and antiviral therapy was significantly negatively correlated (P<0.05).Conclusion Hepatitis B and hepatitis C patients should abstain from alcohol,and insist on antiviral therapy intervention early.Hepatitis B patients with a family history of liver cancer should be alert to the risk of liver cancer and pay close attention to monitoring and follow-up to improve the life quality of patients.
作者
王丽
王鹏
李旭东
Wang Li;Wang Peng;Li Xudong(Xinxiang Infectious Disease Hospital,X inxiang 453000,Henan,China)
出处
《临床心身疾病杂志》
CAS
2019年第1期51-54,共4页
Journal of Clinical Psychosomatic Diseases
关键词
乙肝
丙肝
肝癌
影响因素
Hepatitis B
hepatitis C
liver cancer
influencing factors
作者简介
王丽,女,49岁,汉族,本科,副主任医师,科主任。主要研究成果:发表专业论文10余篇。研究方向:传染性疾病与肝病的诊断与治疗。
