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桑菊饮联合阿奇霉素治疗小儿肺炎支原体感染的疗效及对血清hs-CRP的影响 被引量:9

Efficacy of Sangju Decoction Combined with Azithromycin in the Treatment of Mycoplasma Pneumoniae Infection in Children and the Effect on Serum hs-CRP
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摘要 目的:研究在阿奇霉素治疗小儿肺炎支原体感染的基础上联合中药方剂桑菊饮加减的临床疗效,并对比中西医结合疗法和单纯西医疗法对血清超敏C反应蛋白(hs-CRP)的影响。方法:将符合标准的60名MP(肺炎支原体)感染的患儿,随机分成观察组和对照组,每组各30例。2组患儿均在治疗前抽取并检测血清hs-CRP的值,然后给予对照组常规的西医处理,观察组则在对照组的基础上联合中药桑菊饮加减,对照组治疗2个疗程,观察组治疗3个疗程。疗程结束后比较2组临床疗效,并复查比较血清hs-CRP水平的变化情况。结果:观察组的临床疗效和血清hsCRP的改善情况均明显优于对照组(P<0.05)。结论:桑菊饮加减联合阿奇霉素不仅能提高小儿肺炎支原体感染临床疗效,还能有效降低血清炎性因子hs-CRP的水平,值得临床应用。 Objective:To study the clinical efficacy of azithromycin in the treatment of children with Mycoplasma pneumoniae infection combined with traditional Chinese medicine prescription Sangjuyin.The effect of Chinese and Western medicine combined with Western medicine on serum high-sensitivity C-reactive protein (hs-CRP)was compared.Methods:60 children (Pneumococcal pneumoniae)infected with the standard were randomly divided into observation group and control group,with 30 cases in each group.Serum hs-CRP values were taken and measured before treatment in both groups.The control group was given conventional Western medicine treatment.The observation group was combined with Chinese herbal medicine Sangju drink on the basis of the control group.The control group was treated for 2 courses.The observation group was treated for 3 courses.After the end of the treatment,the clinical effects of the two groups were compared,and the changes of serum hs-CRP levels were compared.Results:The clinical efficacy of the observation group and the improvement of serum hs-CRP were significantly better than the control group (P<0.05).Conclusion:Sangju drink combined with azithromycin can not only improve the clinical efficacy of Mycoplasma pneumoniae infection,but also effectively reduce the level of serum inflammatory factor hs-CRP,which is worthy of clinical application.
作者 项李娥 尚莉丽 张建文 XIANG Li 'e;SHANG Lili;ZHANG Jianwen(The First Affiliated Hospital of Anhui University of Chinese Medicine,Anhui Hefei 230031,China;Anhui University of Chinese Medicine,Anhui Hefei 230038,China)
出处 《中医药临床杂志》 2019年第1期120-123,共4页 Clinical Journal of Traditional Chinese Medicine
基金 安徽中医药大学科研项目(2016fy032) 安徽省省级中医发展专项资金项目(卫办秘[2015]404号)尚莉丽名老中医工作室 安徽省高等学校省级质量工程项目(皖教秘高[2016]108号)尚莉丽名师工作室(2016msgzs048)
关键词 桑菊饮 阿奇霉素 肺炎支原体感染 超敏C反应蛋白 Sangju drink Azithromycin Mycoplasma pneumoniae infection Hypersensitive C-reactive protein
作者简介 项李娥(1986-),女,医学硕士,主治医师。研究方向:中西医结合防治小儿呼吸系统疾病。E—mail:438569247@qq.com;通讯作者:尚莉丽(1963-),女,主任医师。研究方向:中医儿科。E-mail:kyksh@126.com.
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