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老年慢性心力衰竭患者胆红素与NT-proBNP、hs-CRP的临床意义 被引量:23

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摘要 目的探讨老年慢性心力衰竭(CHF)患者血清胆红素与N末端B型脑钠肽前体(NT-proBNP)、超敏C反应蛋白(hs-CRP)的临床意义。方法将90例老年CHF患者(CHF组)纳入该研究,根据美国纽约心脏协会(NYHA)标准分为Ⅱ、Ⅲ、Ⅳ级亚组,选择47例健康老年人为对照组,测定各组的血清胆红素与NTproBNP、hs-CRP的水平。结果 CHF组血清胆红素、NT-proBNP、hs-CRP水平高于对照组(P<0.05)。CHF各亚组的胆红素、NT-proBNP及hs-CRP表达水平比较,差异有统计学意义(P<0.05);Pearson相关性分析发现总胆红素、直接胆红素、间接胆红素水平与NT-proBNP水平呈正相关(P<0.05);总胆红素、直接胆红素、间接胆红素水平与hs-CRP、左心室的射血分数(LVEF)水平呈负相关(P<0.05)。结论胆红素与NTproBNP、hs-CRP有相关性,有助于心功能状态的评估。
作者 何凯 张伦碧
出处 《重庆医学》 CAS 2019年第1期156-158,共3页 Chongqing medicine
基金 重庆市卫生和计划生育委员会科研项目(20143020)
作者简介 何凯(1976-),主治医师,硕士,主要从事心力衰竭机制研究;通信作者:张伦碧,E-mail:541996695@qq.com。
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