摘要
目的:观察大鼠急性创伤应激(ATS)后心电图变化,研究QT间期变化与室性心律失常(VA)的关系。方法:建立截肢ATS模型,单导联心电图机记录10只ATS大鼠Ⅱ导联心电图。结果:ATS后大鼠心率明显增快,ATS早期大鼠QTc间期呈先缩短后延长的变化规律,VA发生率及VA评分明显增高,特别是QTc缩短的早期阶段更为明显。结论:ATS早期可出现心电不稳现象,为ATS后VA防治的重点阶段。
Objective: To investigate the relationship between QT interval changes and ventricular arrhythmia(VA)through the changes of electrocardiogram after acute traumatic stress(ATS)in rats. Methods:An amputation ATS model was established. A single-lead electrocardiograph was used to record the electrocardiogram in 10 ATS rats.Results:The heart rate ofrats increased significantly after ATS. The QTc interval of early ATS rats was prolonged after a short period of shortening,and the incidence of VA and VA score were significantly increased,especially in the early stage of QTc shortening period. Conclusion:The early stage of ATS can cause ECG instability,which is the key stage of VA prevention and treatment after ATS.
作者
王莉
范先英
陈日超
周庆
杨宇萍
陈芳
徐丽欣
司明华
陈华
WANG Li;FAN Xian-ying;CHEN Ri-chao;ZHOU Qing;YANG Yu-ping;CHEN Fang;XU Li-Xin;SI Ming-hua;CHEN Hua(The Second Affiliated Hospital of Guilin Medical College,Gui Lin,530022)
出处
《岭南急诊医学杂志》
2018年第6期521-522,532,共3页
Lingnan Journal of Emergency Medicine
基金
广西自然科学基金资助项目(2015GXNSFAA139207)
桂林市科学研究与技术开发计划项目合同(20170109-49)
广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z20170872)
关键词
应激
创伤
心律失常
心电图
stress
trauma
arrhythmia
electrocardiogram
作者简介
通讯作者:陈华.
