摘要
目的分析2015-2017年四川省内江市疑似预防接种异常反应(adverse events following immunization,AEFI)的发生特征。方法收集2015-2017年四川省内江市5个县区通过全国AEFI监测系统报告的AEFI个案资料,共1357例。采用描述流行病学方法对AEFI报告情况、时间分布、年龄分布、发病时间间隔分布、分类分布、临床症状分布、临床诊断分布、接种疫苗分布等指标进行分析。结果2015—2017年,内江市共报告AEFI病例1357例,其中6至8月报告病例数较多(38.39%,521/1357),<1岁组婴幼儿较多(32.20%,532/1357)。接种疫苗后0-1d发病的病例最多(89.39%,1213/1357),一般反应较多(88.95%,1207/1357),临床症状以发热(52.76%,716/1357)、局部红肿(46.43%,630/1357)、局部硬结(30.07%,408/1357)为主。结论内江市AEFI报告病例数以6至8月居多,常发生在小年龄儿童和接种早期,发生分类以一般反应为主,症状以发热、红肿、硬结为主。
Objective To analyze the occurrence of adverse event following immunization (AEFI)in Neijiang city of Sichuan province during 2015-2017.Methods A total of 1357 cases of AEFI reported by the national AEFI surveillance system in 5counties and districts of Neijiang city from 2015 to 2017 were collected.Descriptive epidemiological methods were used to analyze AEFI reports,distributions of time,age and time interval,classification,clinical symptoms,clinical diagnosis and vaccine.Results From 2015 to 2017,a total of 1357cases of AEFI were reported in Neijiang city.The number of cases reported from June to August was more (38.39%,521/1357).The number of infants and young children in the <1-year-old group was more (32.20%,532/1357).Within 0-1day after inoculation,more cases (89.39%, 1213/1357) and more general reactions (88.95%,1207/1357)occurred.The clinical symptoms were manifested as follows:fever (52.76%,716/1357),swelling (46.43%,630/1357)and sclerosis (30.07%, 408/1357).Conclusions The number of AEFI cases reported in Neijiang city was mainly from June to August.AEFI commonly oecured in young children and in early stage of vaccination.The main type of AEFI was general reaction.The main symptoms were fever,swelling and sclerosis.
作者
刘宣辰
栾荣生
Liu Xuanchen;Luan Rongsheng(Huaxi Public Health,Sichuan University,Chengdu 610041,China;Department of Operations and Scientific Research,Neijiang Center for Disease Control and Prevention,Sichuan Province)
出处
《国际病毒学杂志》
2018年第6期423-425,共3页
International Journal of Virology
关键词
疫苗
接种
预防接种异常反应
人群监测
Vaccines
Vaccination
Adverse events following immunization
Population surveillance
作者简介
通信作者:栾荣生,Email:luan_rs@scu.edu.cn
