摘要
目的 寻找一种客观实用的方法 ,预测脑室积血 (IVH)并发急性梗阻性脑积水 (AOH)的发生概率。方法 用原Graeb及修改Graeb 2种评分标准 ,对积血为主要部位的第四脑室组 15例、第三脑室组 19例及基底节出血所致侧脑室组 3 8例 ,根据有无AOH ,用四格表确切概率法及Logistic回归分析法分析积分与脑积水的关系。结果 按修改Graeb标准在敏感性和特异性二曲线交点时 ,敏感性、特异性、误诊率、漏诊率、诊断效率、Youclen和K值分别为 0 95 2、0 90、0 1、0 0 4 8、0 93、0 85 2和0 85。用Logistic回归分析 5~ 12分者并发AOH的概率分别为 :0 0 2、0 0 7、0 2 6、0 62、0 88、0 97、0 99及 1 0。结论 修改Graeb标准能较好地预测第三、第四脑室及幕上出血量小于 3 0ml所致IVH并发AOH的发生概率。
Objective To investigate a practical and useful method for predicting probabilities of acu te obstructive hydrocephalus (AOH) after intraventricular hemorrhage(IVH). Methods 72 patients with IVH in three locations were stud ied .The AOH,including the fourth ventricular group 15 cases, the third ventricular group 19 cases, and 38 cases in lateral ventricular group with volume less than 30 ml i n basilar ganglion region were analysed.The grading of IVH were assessed usi ng Graeb and modified Graeb criteria . The sensitivity (Se), specificity (Sp),f als e positive probability (α),false negative probability (β), diagnostic effic ie ncy (DE),Kappa value(K) and diagnostic index(DI) were studied by exact pro babil ities in 2×2 tables in each group. The probabilities of AOH were studied by L ogistic regression. Results In modified criteria group,at cross-point of c urv es of Se and Sp, the parameters Se,Sp,α,β,DE,K and DI were distributed in id eal statistical range, and probability of AOH from 5 to 12 was 0.02 ,0.07, 0.26 ,0.62 ,0.88, 0.97, 0.99 and 1.0. Conclusion The modified Graeb crite ria were suggested to be a more useful method to predict the probabilities of A OH of IVH .
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2001年第5期273-275,共3页
Chinese Journal of Neurology