摘要
目的 :探讨百忧解对抑郁症伴发的焦虑情绪和疗效。方法 :对不伴焦虑情绪和伴焦虑情绪的抑郁症患者都予以百忧解治疗 ,在治疗前、治疗后 2、4、6周进行HAMD2 4 、HAMA、MADS ,CGI等量表评定。通过各量表减分、减分率的组内、组间比较 ,观察百忧解对抑郁症伴发的焦虑情绪是否有效。结果 :①治疗前伴焦虑组各量表分值较不伴焦虑组高 (P <0 0 5 )。②试验结束时 ,HAMD2 4 减分率≥ 5 0 %的为 76 % (38/ 5 0 ) ,与MADS一致 (P >0 0 5 )。从各量表因子分分析来看 ,治疗后都有不同程度减分 (P <0 0 5 )。且伴焦虑情绪组 5 3 8%的患者HAMA减分≥ 5 0 % ,入组时与试验结束时HAMA平均分有显著性差异。结论 :百忧解对抑郁症伴发的焦虑情绪有效。
Objective:To evaluate the effect of prozac in anxiety mood in depression.Method:nonanxious depressive patients and anxious depressive patients were treated with prozac and the scales HAMD 24 ?HAMA?MADS?CGI were used for evaluation before and after treatment 2?4?6 weeks.The results were compared intra group and intergroups.Results:After this trial finished,The baseline of HAMA total score was reduced at least 50% in 53 8%(17/26) anxious depressive patients.he mean score of HAMA was 25 27±5 67 before treatment but 12 36±1 69 after being treated 6 weeks( P <0 05).The baseline total score of HAMD 24 was reduced in nonanxious depressive and anxious depressive patients both,No statistics significant difference was founded between the two groups( P >0 05).All the subfactor scores of HAMD 24 were decreased after 6 weeks therapy( P <0 05).And the scores of MADS?CGI decreased significantly in both group( P <0 05).Conclusion:Prozac is effective in the treatment of anxicty mood with depression.
出处
《华西医学》
CAS
2001年第4期422-424,共3页
West China Medical Journal
