摘要
目的 :探讨心理社会因素对鼻咽癌患者影响的作用规律和早期识别方法 ,为早期发现、早期诊断和早期治疗服务。方法 :通过 1∶1配对临床流行病学调查方法收集资料建立数据库文件 ,在PTMMX 2 0 0 0型微机上完成配对Logistic回归和判别分析。结果 :在α =0 .0 5水准 ,发现X2 (嗜烟习惯 )、X8(家用燃料种类 )、X12 (爱生闷气 )、X13(病后情绪低落恐惧 )和X15(病后得不到亲人关照和心理满足 )计 5个差异有显著性的变量 (P <0 .0 5 )进入方程 :LogitP=ai- 66.7362X15+ 91.386 6X13 - 3.7985X12 - 4.0 142X8- 5 .6 0 6 3X2 ;在此基础上建立了鼻咽癌和非鼻咽癌判别诊断模型。判别诊断与临床诊断总的符合率高达 93 .33% ,其中对鼻咽癌和非鼻咽癌判别符合率分别为 95 .0 0 %和 91.6 7% ,总的误判率为 6 .6 7%。结论 :所建数学模型具有一定临床意义 ,从是否患肿瘤角度提出的健康模式假设 ,尚待进一步研究。
In order to probe into the identifying methods and effects of psychosocial factors on patients with carcinoma of nasopnarynx,120 cases with carcinoma of nasopharynx and their matched control were surveyed by the method of clinical epidemiology in paired design of 1∶1 case control way.The matched logistic regression and discriminant analysis were made.The 5 variables were terminally selected into the matched logistic regression equation at α level 0.05.These variables were as follows:X 2,indulge in cigarettes;X 8,the family fuel type;X 12 ,the depressed emotion;X 13 ,fear after sickness and X 15 ,condition without care and satisfaction from benignity and friends after sickness.The matched logistic regression equation was as follows:Logit P=ai-66.7362X 15 +91.3866X 13 -3.7985X 12 -54.0142X 8-5.6063X 2.To sum up,it was found that these variables were important factors for restoring to health in patients with carcinoma of nasopharynx.On this basis the discriminant analysis of two type was made,and discriminant functions were established and it was significant for clinical diagnosis and therapy.
出处
《武汉大学学报（医学版）》
CAS
2001年第1期32-34,共3页
Medical Journal of Wuhan University
关键词
鼻咽肿瘤
心理社会因素
变量分析
nasopharyngeal neoplasms
psychosocial factor
analysis of variables
