摘要
为了阐明湿热环境对机体抗病力的影响机理 ,本实验以兔为实验对象 ,观察了湿热环境对体内一种重要的杀菌抗内毒素物质———杀菌 通透性增加蛋白mRNA表达的影响。结果 :发现湿热环境能使兔在内毒素刺激下杀菌 通透性增加蛋白mRNA表达减少 ,这可能是湿热致病和湿热证缠绵难愈的病理机制之一。
To investigate the mechanism of damp\|heat environment affects resistance to disease,an experiment aimed to observe the affection of damp\|heat environment on the lipopolysaccharide induced batericidal/permeability\|increasing protein mRNA expression was practiced. The result is damp\|heat environment can inbibit lipopolysaccharide induced batericidal/permeability\|increasing protein mRNA expression. This may be the partial mechanism through which damp\|heat environment down\|regulate resistance to disease,and can partially explain why Damp\|Heat Syndrome have long duration.
出处
《中国中医基础医学杂志》
CAS
CSCD
2001年第9期40-42,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
广东省中医药管理局课题 (NO 9832 5 )
关键词
湿热
内毒素
杀菌
通透性增加蛋白
mRNA
Damp-Heat Environment
Lipopolysaccharide
Bactericida-Permeability-Increasing Protein
