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成都市城区儿童幽门螺杆菌感染调查 被引量:11

Epidemiology of Helicobacter Pylori Infection in Children of Urban Chengdu
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摘要 目的通过调查分析成都市城区儿童幽门螺杆菌(Helicobacter pylori,Hp)感染的流行病学特征为防治提供参考。方法对成都市城区0~16岁共907例儿童进行粪便Hp抗原检测,并同时进行问卷调查,对Hp感染的相关因素进行x2检验及多因素Logistic回归分析。结果成都市城区儿童Hp平均自然感染率为6.3%,新生儿期即存在感染,感染率为8.33%,10岁后感染率明显升高,达到17.4%。经χ2检验及多因素Logistic回归分析显示,Hp感染与年龄、家庭成员有消化道疾病、吸允手指相关,与同居人口数可能相关。结论成都市城区非儿童Hp感染高发地区,生活条件及卫生习惯是Hp感染的重要危险因素,预防应有针对性进行。 Objective To investigate the prevalence of helicobacter pylori (Hp) infection in children living in urban areas of Chengdu. Methods A total of 907 healthy children aged 0 -16 years were tested for the presence of Hp stool antigens ( HpSA), and a survey was conducted by questionnaire concurrently. Results The prevalence of Hp infection was 6. 3%. Hp infection might be acquired in the neonatal period, with 8. 33% positive. The infection rate increased significantly after 10 years old, reaching to as high as 17.4%. Chi - square test and multiple factor Logistic revealed that the prevalence of H. pylori infection was associated with age, family members with a digestive disease history and finger sucking habits of the children, and might also associated with overcrowding in the house. Conclusion Poor living conditions and bad health habits are important risk factors of Hp infection and thus targeted prevention measures should be implemented.
出处 《预防医学情报杂志》 CAS 2014年第5期349-352,共4页 Journal of Preventive Medicine Information
基金 "十一五"国家科技支撑计划课题(项目编号:2007BAI04B02)
关键词 幽门螺杆菌 粪便抗原 儿童 流行病学 helicobacter pylori HpSA children epidemiology
作者简介 王丽媛(1981-),女,在读研究生,主治医师,消化儿科 通讯作者:毛萌
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