摘要
目的：探讨天然促智药复方──补肾益智方含药血清对培养海马神经元过度凋亡的抑制作用。方法：取补肾益智方治疗组及各对照组大鼠的血清进行海马神经元培养，荧光标记，计量分析。结果：各组血清培养的海马神经元凋亡率，中药组明显低于模型组、石杉碱甲（ＨｕｐＡ）组明显高于青年组，与老年正常组没有明显差异。结论：补肾益智方含药血清可减少培养海马神经元的过度调亡。
OBJECTIVE: To explore the effect of complex prescription of natural nootropic drugs, Bushenyizhi decoction, on the inhibition mechanism of apoptosis of cultured hippocampal neuron. METHOD: Hippocampal neurons were cultured with the serum of the treated and the controls; and fluorescent labeling and statistics analysis were carried on. RESULTS: Apoptosis rate of the serum of treated was significant lower than that of the model and the Hup A, and higher than that of the young, CONCLUSION: The serum of the treated can inhibit the apoptosis of culture hippocampal neurons.
出处
《世界科学技术-中药现代化》
2001年第1期26-28,共3页
World Science and Technology(Modernization of Traditional Chinese Medicine)
基金
国家"九五"重点科技攻关专题!(No96-906-09-02)
教育部高校骨干教师基金
科技部生命科学发展中心博士基金!(No
