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联合检测血清CA-125、AFP、D-二聚体对胎盘早剥早期诊断的临床价值 被引量:7

The clinical value of the combined detection of maternal serum CA-125,AFP,D-Dimer in early diagnosis for placental abruption
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摘要 目的探讨联合检测孕妇血清中CA-125、AFP、D-二聚体水平对胎盘早剥早期诊断的临床价值。方法选择在该院产检并分娩的200例孕妇为研究对象,分为胎盘早剥组65例、高危组72例、健康对照组63例。分别采用电化学发光法和免疫比浊法检测孕妇血清CA-125、AFP、D-二聚体,比较三组检测结果的差异。结果胎盘早剥组CA-125、AFP、D-二聚体水平明显高于高危组与健康对照组(P<0.05),高危组CA-125、AFP、D-二聚体水平明显高于健康对照组(P<0.05)。结论孕妇血清中CA-125、AFP、D-二聚体联合检测对于胎盘早剥早期预测有一定临床价值。 【Objective】To study the clinical value of the combined detection of maternal serum CA-125, AFP, D-Dimer in early diagnosis for placental abruption and provide the more evidences for early diagnosis for placental abruption. 【Methods】The 200 pregnants received labor examination and delivery in our hospital were regarded as the research subjects and then divided into the placental abruption group(65 cases), risk factors group(72 cases), control group(63 cases). The three serum parameters detection of CA-125, AFP, D-Dimer in the three groups were assayed and compared. The serum samples were extracted by expert operation and were assayed by the same kit and instrument. 【Results】Compared with the risk factors group and the control group, the levels of CA-125, AFP, DDimer were significantly increased in the placental abruption group(P &lt;0.05); compared with the control group,the levels of CA-125, AFP, D-Dimer were significantly increased in the risk factors group(P &lt;0.05).【Conclusion】The combined detection of maternal serum CA-125, AFP, D-Dimer can predict the early placental abruption and is worthy of clinical promotion.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2014年第10期37-39,共3页 China Journal of Modern Medicine
基金 温州市卫生局基金项目(No:2011B063)
关键词 CA-125 AFP D-二聚体 胎盘早剥 CA-125 AFP D-Dimer placental abruption
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