摘要
目的 建立白酒中18种邻苯二甲酸酯（PAEs）的气相色谱-串联质谱（GC-MS／MS）测定方法。方法 样品中加入PAEs同位素内标，调整样品的酒精度，以甲苯萃取，采用GC—MS／MS以多反应监测模式（MRM）测定。结果 苯二甲酸二异壬酯（DINP）、邻苯二甲酸二异癸酯（DIDP）在0．1～10μg／ml，其他16种PAEs在0．01～1．0μg／ml范围内呈良好线性关系，r^2≥0．991；方法检出限为3．1～150．0μg／L，定量限为9．9～500．0μg／L；在3个加标水平下，样品平均回收率为98．5％～119．8％，RSD为0．6％～15．6％。结论本方法提高了白酒中PAEs检测的特异性，适合于白酒中多组分PAEs的同时检测。
Objective A gas chromatography-tandem mass spectrometry （GC-MS/MS） method for the detection of 18 phthalates （PAEs） in white spirits was developed. Methods The samples were spiked with isotope internal standards, adjusted by alcohol concentration, and finally extracted with toluene. The supernatant were determined by GC-MS/MS. Results The calibration curves of 18 phthalates obtained were linear with correlation coefficients above 0. 991. It was effective in the determination of phthalates in white spirits. The limits of detection were 3.1-150.0 μg/L and the limits of quantification were 9.9-500. 0μg/L. The recoveries were 98.5% -119. 8% with the RSD of 0. 6%-15.6% at different spiking levels. Conclusion The method improved the specificity for PAEs detection in white spirits and was applicable for multi-component PAEs detection.
出处
《中国食品卫生杂志》
北大核心
2014年第3期249-254,共6页
Chinese Journal of Food Hygiene
基金
食品接触材料中有害物质迁移量关键检测技术研究(2011BAK10B05-02)
关键词
白酒
邻苯二甲酸酯
同位素内标稀释技术
气相色谱-串联质谱法
食品污染物
塑化剂
食品安全
White spirits
phthalates
isotope internal standards diluted technology
gas chromatography-tandem mass spectrometry
food contaminant
plasticizing agent
food safety
作者简介
苗宏健 男 助理研究员 研究方向为食品接触材料中有害物质的检测技术 E-mail：mono_1984@163．com
通讯作者：赵云峰 男 研究员 研究方向为食品理化检测技术 E-mail：zhaoyi703@126．com
