摘要
【目的】研究用微乳提取补骨脂中补骨脂素和异补骨脂素。【方法】考察微乳处方,选取可以形成稳定、澄清、微乳区域较大的组方制备微乳;采用HPLC法测定微乳提取物中补骨脂素和异补骨脂素的含量。【结果】在拟定微乳处方中,微乳提取的补骨脂素和异补骨脂素的总量高于乙醇提取物。【结论】较传统提取溶剂,微乳能有效地提高补骨脂素和异补骨脂素的提取率。
[Objective ] To study the extraction of psoralen and isopsoralen in fructus psoraleae by microemulsion. [ Methods ] To investigate the formulation of microemulsion, the formulations used in extraction were selected from microemulsions area determinate through mixture experiments. The contents of psoralen and isopsoralen in microemulsion extraction were determined by HPLC. [ Resuits ] Among the investigated microemulsions, the total contents of psoralen and isopsoralen in microemulsion extraction were higher than those in ethanol extraction. [ Conclusion ] Compared with traditional solvent, microemulsion could effectively improve the extraction rate of psoralen and isopsoralen in fructus psoraleae.
出处
《武警后勤学院学报（医学版）》
CAS
2014年第4期309-310,324,F0003,共4页
Journal of Logistics University of PAP（Medical Sciences）
基金
湖南省中医药科研计划项目(201163)
关键词
微乳
补骨脂
补骨脂素
异补骨脂素
Microemulsion
Fructus Psoraleae
Psoralen
Isopsoralen
作者简介
[作者简介]周平兰，硕士，副主任药师，主要从事中药制剂的研究。
[通信作者]冯欲静，本科，实验师，主要从事中药制剂的研究，E—mail：afengyujing@gmail．com。
