摘要
目的：探讨影响极低出生体重早产儿（WLBWI）早期（出生1～4周）体重增长相关影响因素。方法：回顾性分析该院2011年1月～2013年1月收治的128例WLBWI的临床资料，并根据患儿住院期间体重增长情况分为低体重增长组32例（日均体重增长〈10g／kg）、适宜体重增长组46例（日均体重增长为10～15g/kg）以及高体重增长组40例（日均体重增长〉15g／kg），并对影响WLBWI体重增长的相关因素进行Logistic回归分析。结果：胎龄、妊娠胎数、母亲妊娠期高血压、子痫前期、住院时间、出生时体重、喂养方法、蛋白摄入达标时间、热量摄入达标时间均可影响WLBWI体重增长。经Logistic单因素分析显示，胎龄、喂养方法、开始喂养时间、蛋白摄人达标时间、热量摄人达标时间是影响WLBWI早期体重增长的独立危险因素。与体重增加适宜组及高体重增长组相比，低体重增长组患儿败血症、新生儿肺炎、支气管发育不良、胆汁淤积症发生率显著上升，差异有统计学意义（P〈0．05），而体重增长适宜组及高体重增长组各并发症发生率无统计学意义（P〉0．05）。结论：早期营养喂养时间及喂养方式对WLBWI体重增加具有重要的作用，改善WLBWI患者早期蛋白质及热量的摄取可改善患儿生长速度，降低患儿并发症发生率，有利于WLBWI患儿预后。
Objective： To explore the related influencing factors of early （ 1 -4 weeks after birth） body weight gain of very low birth weight premature infants （WLBWI） . Methods： The clinical data of 128 cases of WLBWI treated in the hospital from January 2011 to January 2013 were analyzed retrospectively, then the infants were divided into low body weight gain group （32 infants, average daily body weight gain 〈 10 g/kg） , appropriate body weight gain group （46 infants, average daily body weight gain： 10 - 15 g/kg） and high body weight gain group （40 infants, average daily body weight gain 〉 15 g/kg） ; the related influencing factors of body weight gain of the infants were analyzed by logistic regression analysis. Results ： The influencing factors of body weight gain of the infants included gestational age, the number of pregnancy, maternal hypertensive disorder complicating pregnancy （ HDCP）, preeclampsia, hospitalization time, birth weight, feeding patterns, the time to reach the standard of protein intake and the time to reach the standard of energy intake. Logistic univariate anal- ysis showed that gestational age, feeding patterns, start feeding time, the time to reach the standard of protein intake and the time to reach the standard of energy intake were independent risk factors affecting early body weight gain of the infants. Compared with appropriate body weight gain group and high body weight gain group, the incidence rates of sepsis, neonatal pneumonia, bronchial dysplasia and cholestasis in low body weight gain group increased significantly （P 〈 0. 05 ）, but there was no statistically significant difference in the incidence rates of a- bove - mentioned complications between appropriate body weight gain group and high body weight gain group （P 〉 0. 05 ） . Conclusion： Early nutritional feeding time and feeding patterns have important impacts on body weight gain of WLBWI patients, which can improve early intakes of proteins and energy and growth speed, reduce the incidence rates of complications, benefit prognosis of these infants.
出处
《中国妇幼保健》
CAS
北大核心
2014年第14期2163-2166,共4页
Maternal and Child Health Care of China
基金
湖北省荆州市卫生局科技项目〔2006-0037〕
关键词
极低出生体重早产儿
体重增长
影响因素
Very low birth weight premature infant
Body weight gain
Influencing factor
作者简介
通讯作者Email：tanjufang_11@126．com
