摘要
上皮性卵巢癌(epithelial ovarian cancer,EOC)是危害妇女健康的隐形杀手,如何早诊断及病情监测是学者研究热点。超声、糖类抗原125是目前诊断监测EOC常用检查。人附睾蛋白4是最近发现的EOC相关因子,其敏感性及特异性均优于超声及糖类抗原125,而三者联合检测可以提高特异性及敏感性,降低假阳性率,是早诊断及监测EOC治疗效果的良好途径。
As epithelial ovarian cancer （EOC） is an invisible killer to female health, early diagnosis and disease monitoring becomes a focus of study. Ultrasound, carbohydrate antigen 125 is current common tests for diagnosing and monitoring EOC. Human epididymis protein 4 （HE4）, a recently discovered EOC-related factor, has better sensitivity and specificity than the ultrasound and the carbohydrate antigen 125. The combination of these three items can improve the sensitivity and specificity to EOC and decline the false positive rate, which is a good way for early diagnosis and monitoring the therapeutic effect of EOC.
出处
《临床医学工程》
2014年第4期535-536,共2页
Clinical Medicine & Engineering
基金
广西壮族自治区卫生厅计划课题(课题编号:Z2013477)
关键词
上皮性卵巢癌
超声
糖类抗原125
人附睾蛋白4
Epithelial ovarian cancer
Ultrasound
Carbohydrate antigen 125
Human epididymis protein 4
作者简介
李丽军（1973-），女，广西桂林人，研究生学历，主治医师．E—mail：bwk3160@163．com
通讯作者：贝朝勇，桂林医学院附属医院（广西桂林541001）。
