摘要
目的探讨三维适形放疗在原发性肝癌综合治疗中的效果.方法选择2007年7月～2010年7月收治的原发性肝癌患者49例,根据肝硬化Child-Pugh分级,A级32例,B级17例,合并门静脉癌栓9例.采用6MV-X线直线加速器进行三维适形放疗,常规放疗每次剂量2Gy,总照射剂量45.4～62.6Gy（平均54.5Gy）.结果完全缓解率为10.2％,部分缓解率为61.2％,无变化率为22.4％,进展率为6.1％,总有效率为71.4％;1、2、3年生存率分别为57.1％、34.6％、16.3％;中位生存期为13.4个月;放射性肝病发生率为4.1％.结论三维适形放疗治疗肝癌效果较好,尤其是对于合并门静脉癌栓的患者,毒副反应可耐受.
Objective To evaluate the effect of three-dimensional conformal radiotherapy in the comprehensive treat- ment of liver carcinoma. Methods 49 patients with primary liver cancer were selected in our hospital from 2008 July to 2010 July,according to the Child-Pugh grading of liver cirrhosis,32 cases of grade A and 17 cases of grade B.There were 9 cases with portal vein tumor thromhus.All the patients were given three- dimensional conformal radiotherapy for 6MV-ray linear accelerator.A dose of conventional radiotherapy was 2 Gy,the dose of total radiation was 45.4-62.6 Gy （mean 54 5 Gy）. Results The complete remission rate was 10.2%,partial remission rate was 61.2%,no change rate was 22.4%,progress rate was 6.1%,total effective rate was 71.4%.1,2,3 year survival rates were 57.1%,34.6% and 16.3% re- spectively.The median survival period was 13.4 months,the radiation hepatitis incidence was 4.1%. Conclusion The efficacy of three-dimensional conformal radiotherapy for liver cancer is better,especially for the patients with combined portal vein tumor thrombus,toxicity can be tolerated.
出处
《中国当代医药》
2014年第11期107-108,共2页
China Modern Medicine
关键词
原发性肝癌
适形放疗
预后
Primary hepatocellular carcinoma
Conformal radiotherapy
Prognosis
