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表皮生长因子受体-酪氨酸激酶抑制剂对非小细胞肺癌患者中枢神经系统转移的疗效 被引量：6

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摘要 肺癌是目前世界上导致肿瘤相关死亡的首要原因，严重威胁着人类的健康，其中非小细胞肺癌（NSCLC）占70％-80％，且80％的NSCLC患者在诊断时已处于疾病晚期（Ⅲb～Ⅳ期）。脑转移是晚期NSCLC常见的转移部位，约10％-25％的患者诊断时已出现中枢神经系统（CNS）转移，在治疗中，40％-50％的患者出现CNS转移。CNS转移主要包括脑转移和脑膜转移，通常表现为颅内压增高，如恶心、呕吐及头痛等；脑转移的部位通常位于脑白质和灰质交界区，
作者 王孟昭 陈闽江
机构地区 中国医学科学院中国协和医科大学北京协和医院呼吸内科
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2014年第3期169-171,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
关键词 中枢神经系统 非小细胞肺癌 转移部位 肺癌患者 酪氨酸激酶抑制剂 表皮生长因子受体 晚期NSCLC 疗效
分类号 R734.2 [医药卫生—肿瘤]
作者简介 通信作者：王孟昭，Email：mengzhaowang@sina．com
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共引文献56

同被引文献57

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引证文献6

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中华结核和呼吸杂志
2014年 第3期

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