摘要
目的:探讨黄葵胶囊治疗早中期糖尿病肾病的临床疗效及对患者血脂的影响。方法:将126例早中期糖尿病肾病患者随机分为对照组与实验组,对照组给予常规治疗,实验组同时接受黄葵胶囊口服。结果:实验组治疗有效率显著优于对照组(P<0.05);治疗后实验组血肌酐、尿素氮、β2微球蛋白、尿白蛋白排泄率及24 h尿蛋白总量显著低于对照组(P<0.05);与对照组比较,实验组血甘油三酯、胆固醇及低密度脂蛋白显著下降(P<0.05);多普勒结果显示实验组治疗后Vs显著降低,Vd显著升高(P<0.05)。结论:黄葵胶囊治疗早中期糖尿病肾病可显著改善肾功能、肾血流并能降低血脂,延缓病情进展。
Objective To explore the effect of huangkui capsule in early and middle stage of diabetic nephropathy patients and the influenee for blood lipid. Methods： 126 cases with early and middle stage of diabetic nephropathy were randomly divided into control group and experience group. Control group were given routine treatment, and experience group received huangkui capsule therapy. Results The effective rate of treatment in experience group was much higher than that in control group （P 〈 0. 05） ; SCr, BUN, U-132MG, urinary albumin excretion rate, the total 24 hour urine protein, TG, TC and LDL-C after treatment in experience group were much lower than those in control group （P 〈 0.05 ） ;Doppler results showed that Vs and Vd after treatment in experience group were superior to control group（P 〈 0.05 ）. Conclusions Huangkui capsule for early and middle stage of diabetic nephropathy patients greatly improve renal function and renal blood flow, decrease the blood lipid and delay the disease progression.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2014年第2期200-201,210,共3页
JOURNAL OF BASIC CHINESE MEDICINE
关键词
糖尿病肾病
黄葵胶囊
肾功能
血脂
Diabetic nephropathy
Huangkui capsule
Renal function
Blood lipid
作者简介
李昭永（1967-），男，贵州毕节人，副主任医师，医学学士，从事中西医结合肾脏病的临床与研究。
