摘要
目的观察血小板抗体产生对血小板输注效果的影响。方法选择本院100例输血患者分为两组,A组患者输注的血小板没有滤除白细胞,B组患者输注的血小板滤除白细胞。检测两组血小板相关抗体(HLA抗体)阳性率和血小板特异性抗体(HPA抗体)阳性率,评估两组血小板输注效果。结果 A组血小板输注无效率为48.9%,B组血小板输注无效率为12.7%,差异有统计学意义(P<0.01)。两组HLA抗体阳性率分别为55.6%和14.5%,差异有统计学意义(P<0.01)。两组HPA抗体阳性率是15.6%和10.9%,差异无统计学意义(P>0.05)。结论输注滤除白细胞的血小板,可以提高血小板的输注效果。
Objective To observe the impact of platelet antibody on platelet transfusion effects. Methods 100 patients in our hospital were divided into two groups,group A was given platelet transfusion without leukocyte depletion,and group B was given platelet transfusion with leukocyte depletion.The HLA antibody positive rate and HPA antibody positive rate were tested to evaluate the effects of platelet transfusion between the two groups.Results The ineffective rate of platelet transfusion in group A and group B was 48.9% and 12.7% respectively,the difference was significant（P 0.01）.The HLA antibody positive rate in group A and group B was 55.6% and 14.5% respectively,the difference was significant（P0.01）. The HPA antibody positive rate in group A and group B was 15.6% and 10.9% respectively,the difference was not significant（P0.05）.Conclusion Leukocyte depletion can improve the effects of platelet transfusion.
出处
《中国当代医药》
2014年第6期184-185,188,共3页
China Modern Medicine
关键词
血小板抗体
血小板输注
白细胞
Platelet antibody
Platelet transfusion
Leukocyte
