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白血病干细胞研究进展

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摘要 髓系白血病是一种具有多分化潜能的异常造血细胞形成的克隆性疾病,以造血干祖细胞的增殖、分化和成熟异常为主要特征。通过对白血病不同亚群进行研究,研究者发现不同群体的白血病细胞功能不同,研究认为白血病干细胞(LSC)与此有关,文章就LSC起源、免疫表型及治疗等方面的研究进展进行综述。
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出处 《中国卫生产业》 2014年第4期188-188,191,共2页 China Health Industry
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  • 1Visvader JE,Lindeman GJ. Cancer stem cells in solid tumours:accumu-lating evidence and unresolved questions[J].Nature Reviews Cancer,2008.755-768.
  • 2Tanturli M,Giuntoli S,Barbetti V. Hypexia selects bortezomib-re-sistant stem cells of chronic myeloid leukemia[J].PLoS One,2011.e17008.
  • 3Gong X,Schwartz PH,Linskey ME. Neural stem/progenitors and glionla stem-like cells have differential sensitivity to chemotherapy[J].NEUROLOGY,2011.1126-1134.
  • 4Kirstetter P,Schuster MB,Bemshchenko O. Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells[J].Cancer Cell,2008.299-310.
  • 5Chen W,Kumar AR,HudsonWA. Malignant transformation initiated by Mll-AF9:gene dosage and critical target cells[J].Cancer Cell,2008.432-440.
  • 6Nicolas G,Marchi E,Vyas P. Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia[J].Cancer Cell,2011.138-152.
  • 7Bereshchenko O,Maneini E,Moore S. Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia initiating cells in C/EBPalpha mutant AML[J].Cancer Cell,2009.390-400.
  • 8Taussig DC,Vargaftig J,Bonnet D. Leukemia initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34-fraction[J].Blood,2010.1976-1984.
  • 9Morisot S,WayI1e AS,Bohana-Kashtan O. High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic 1 eukemias[J].LEUKEMIA,2010.1859-1866.
  • 10Adams JM,Kelly PN,Dakic A. Role of"cancer stem cells"and cell survival in tumor development and maintenance[J].Cold Spring Harbor Symposia on Quantitative Biology,2008.451-459.

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