摘要
目的观察宫腔镜下子宫内膜息肉电切术后应用屈螺酮炔雌醇片(优思明)治疗和预防子宫内膜息肉复发的临床疗效。方法子宫内膜息肉患者106例,随机分为2组,观察组53例,行子宫内膜息肉电切术后口服优思明治疗3个周期;对照组53例,行子宫内膜息肉电切术后未用药物治疗。随访6个月,观察比较2组治疗效果及复发情况。结果观察组月经改善的显效率、总有效率均高于对照组(73.6%vs.45.3%,94.3%vs.81.1%),差异有统计学意义(P<0.05):观察组子宫内膜息肉复发率为7.5%低于照组的24.5%(P<0.05)。2组均未发生并发症,观察组于服药初期出现轻微恶心3例(5.7%),烦躁、易怒等情绪波动4例(7.5%),均自行缓解。结论宫腔镜下子宫内膜息肉电切术后联合应用优思明,可有效恢复正常月经,降低子宫内膜息肉复发率,不良反应少,值得临床推广。
Objective To observe effcicacy of polyp resection under hysteroscopic resection combined with application drospirenone ethinyl estradiol tablets（Yasmin） in treatment and prevention of endometrial polyp recurrence.Methods106 patients with endometrial polyps were randomly divided into two groups,53 cases in the observation group,received resection of endometrial polyps and Yasmin oral treatment of three cycles;53 cases in the control group,only received resection of endometrial polyps.Follow-up of six months,the treatment effect and recurrence was observed and compared between the two groups.Results Significant improvement in the efficiency of the menstrual and the total effective rate were found in observation group,which were better than the control group,the difference was statistically significant（P 0.05）（73.6%vs.45.3%,94.3%vs.81.1%）;Observation groups endometrial polyp recurrence rate was 7.5%,lower than the control group of 24.5%（P 0.05）.Complications in the two groups did not occur,the observation group had mild nausea in 3 cases（5.7%）,irritability,mood swings,irritability and other in 4 cases（7.5%）,were spontaneous relieved.Conclusion Hysteroscopic endometrial polyp resection combined with Yasmin,which can effectively restore normal menstruation,reduce endometrial polyp recurrence rate,fewer adverse reactions,worthy of promotion.
出处
《疑难病杂志》
CAS
2014年第2期180-182,共3页
Chinese Journal of Difficult and Complicated Cases
关键词
子宫内膜息肉
息肉切除术
宫腔镜
屈螺酮炔雌醇片
Endometrial polyps
Polyp resection
hysteroscopic
Drospirenone ethinyl estradiol tablets
作者简介
通信作者：王彦萍，E—mail：fengxueli．18@163．com
