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肺孤立性磨玻璃密度结节的超高分辨力CT表现及与病理的相关性 被引量:34

Study on solitary pulmonary ground-glass opacity nodule with ultra high resolution CT correlated with pathology
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摘要 目的:探讨肺孤立性磨玻璃密度结节的超高分辨力CT表现及与病理的相关性。方法:搜集经超高分辨力CT(UHRCT)检出并有病理结果的孤立性肺部磨玻璃密度结节(fGGN)72例,72例病灶最大径均≤2cm,回顾性分析其UHRCT表现,并与病理进行对照研究。结果:72例fGGN中纯磨玻璃密度结节(pGGN)20例,混合磨玻璃密度结节(mGGN)52例。20例pGGN中良性病变8例(40%,8/20),其中炎症3例,局灶纤维化3例,间质或肺泡上皮增生2例;不典型腺瘤样增生(AAH)6例(30%,6/20),细支气管肺泡癌(BAC)6例(30%,6/20)。52例mGGN中良性病变2例(3.85%,2/52),其中慢性炎症1例,肺泡内出血1例;恶性病变50例(96.15%,50/52),其中BAC10例,含BAC的腺癌35例,不含BAC的腺癌5例。结论:超高分辨力CT影像上,pGGN的病理诊断以良性病变、AAH或BAC为主,而mGGN则大多为BAC及肺小腺癌。 Objective:To investigate ultra high resolution CT (UHRCT) findings of solitary pulmonary ground glass opacity (GGO) nodule correlating with pathology. Methods: 72 pathologically proved focal ground glass opacity (fGGO) nodules detected by UHRCT were recruited, with the maximum diameter ≤2cm. The UHRCT findings were retrospectively analyzed and correlated with pathology. Results:Of the 72 fGGO nodules,there were 20 pure GGO (pGGO) and 52 mixed GGO (mGGO). 8 (40% ,8/20) were benign lesions among the 20 pGGO nodules (40% ,8/20) ,including inflammation (n= 3 ), focal fibrosis (n= 3) interstitial or alveolar epithelial hyperplasia (n= 2) ; six (30 %, 6/20) were atypical hyperplasia; six (30 %, 6/20) were bronchilolalveolar carcinoma (BAC). There were 2 cases (3.85 %,2/52) of benign lesions among 52 ca- ses of mGGO,including chronic inflammation,and alveolar hemorrhage for one case each;50 cases (96. 15% ,50/52) of mG- GO nodules were malignant lesions,including BAC (n= 10),small pulmonary adenocarcinoma with BAC components (n= 35), and small pulmonary adenocarcinoma without BAC components (n= 5). Concluslon:The pathology of pGGO nodules on UHRCT were mainly benign lesions, AAH or BAC;most of the mGGO nodules were BAC and small pulmonary adenocarci- noma.
出处 《放射学实践》 2014年第1期57-60,共4页 Radiologic Practice
基金 上海市卫生局科研课题(No.20114189) 上海市科学技术委员会课题(No.124119a0100)
关键词 磨玻璃密度结节 肺肿瘤 体层摄影术 X线计算机 病理学 Ground glass nodule Lung neoplasms Tomography,X-ray computed Pathology
作者简介 陈群慧(1969-)女,浙江温岭人,硕士,副主任医师,主要从事胸部影像学诊断工作。 通讯作者:叶剑定,E-mail:y@anding@126.com
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