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老年糖尿病患者合并高血压的危险因素及随访分析 被引量:3

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摘要 目的探讨与分析老年2型糖尿病患者并发高血压的危险因素。方法 2011年1月-2013年1月收治的200例2型糖尿病患者为研究对象,根据其是否合并高血压将其分为观察组118例和对照组82例,对两组的临床资料进行比较分析,探讨影响2型糖尿病合并高血压的危险因素。结果观察组的年龄(68.96±11.62)岁,对照组为(54.76±14.07),观察组高于对照组,病程观察组为(8.23±4.27)年,对照组为(4.34±2.52)年,观察组病程长于对照组,HbAlc水平观察组为(12.64±3.16),对照组为(9.53±1.740),观察组高于对照组,吸烟比例及合并糖尿病肾病发生率观察组分别为25.42%,40.67%,对照组分别为13.41%、25.61%,观察组也高于对照组,差异具有统计学意义(P<0.05)。Logistic回归分析结果显示糖尿病合并高血压的发生与年龄、HbAlc、吸烟、合并糖尿病肾病有关。结论年龄、HbAlc、吸烟、合并糖尿病肾病为老年糖尿病患者合并高血压的危险因素,对该类因素的控制时预防高血压发生的关键。
出处 《当代医学》 2013年第36期47-48,共2页 Contemporary Medicine
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  • 1Boman K,Gerdts E, Wachtell K, et al. Exercise and cardiovascular outcomes in hypertensive patients in relation to structure and function of left ventricular hypertrophy: the LIFE study. Eur J Cardiovasc Prev Rehabil, 2009,16 : 242-248.
  • 2Noblat ACB,Lopes MB, Lopes GB, et al. Complications of hypertensiun in men and women seen in a referral outpatient care unit. Arq Bras Cardiol, 2004,83 : 314-319.
  • 3Redon J, Cea Calvo L, Lozano JV, et al. Kidney function and cardiovascular disease in the hypertensive population: the ERIC-HTA study. J Hypertens, 2006,24:663-669.
  • 4Takahashia M,Takahashia Y,Takahashi K,et al.Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes.FEBS Letters,2008,582:573-578.
  • 5Bozaoglu K,Bolton K,McMillan J,et al.Chemerin is a novel adipokine associated with obesity and metabolic syndrome.Endocrinology,2007,148:4687-4694.
  • 6ten Brinke R,Dekker N,de Groot M,et al.Lowering HbA1c in type 2 diabetics results in reduced risk of coronary heart disease and all-cause mortality.Prim Care Diabetes,2008,2:45-49.
  • 7Roh SG,Song SH,Choi KC,et al.Chemerin-a new adipokine that modulates adipogenesis via its own receptor.Biochem Biophys Res Commun,2007,362:1013-1018.
  • 8Belmadani S,Zerfaoui M,Boulares HA,et al.Microvessel vascular smooth muscle cells contribute to collagen type 1 deposition through ERK1/2 MAP kinase,αvβ3-integrin,and TGF-β1 in response to ANG Ⅱ and high glucose.Am J Physiol Heart Circ Physiol,2008,295:H69-H76.
  • 9Jing L,Zhang JZ,Zhao L,et al.High-expression of transforming growth factor beta1 and phosphorylation of extracellular signal-regulated protein kinase in vascular smooth muscle cells from aorta and renal arterioles of spontaneous hypertension rats.Clin Exp Hypertens,2007,29:107-117.
  • 10Touyz RM,He G,El Mabrouk M,et al.p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotansin Ⅱ in SHR but not in WKY.Hypertension,2001,37:574-580.

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  • 1赵红梅,林正旭.硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的临床疗效[J].求医问药(下半月),2013(7):15-15. 被引量:6
  • 2赵林双,廖玉华,向光大,王敏,侯洁,乐岭,孙慧玲,周子华.缬沙坦治疗抗血管紧张素Ⅱ1型受体自身抗体阳性的高血压合并糖尿病肾病的疗效[J].中华高血压杂志,2007,15(6):469-472. 被引量:23
  • 3Alzaim M.Vitamin D and gestational diabetes mellitus[J].Nutrition Reviews,2013,71(3):158-167.
  • 4Canadian Diabetes Association Clinical Practice Guidelines Expert Committee,EkoéJ M,Punthakee Z,et al.Screening for type 1 and type 2 diabetes[J].Canadian Journal of Diabetes,2013(8):561-567.
  • 5Luk AOY,Ma RCW,Lau ESH,et al.Risk association of Hb A1c variability with chronic kidney disease and cardiovascular disease in type 2 diabetes:Prospective analysis of the Hong Kong Diabetes Registry[J].Diabetes/metabolism Research&Reviews,2013,29(5):384-390.
  • 6Lipska K J,Warton E M,Huang E S,et al.Hb A1c and risk of severe hypoglycemia in type 2 diabetes:the Diabetes and Aging Study.[J].Diabetes Care,2013,36(11):3535-3542.
  • 7Neumark A S,Brudin L,Neumark T.Adherence to national diabetes guidelines through monitoring quality indicators-A comparison of three types of care for the elderly with special emphasis on Hb A1c[J].Primary Care Diabetes,2015,11(6):344-350.
  • 8Smith G,Hayes L.Diabetes in the elderly living in care homes.[J].Revista Clínica Espaola,2014,214(1):517-518.
  • 9Hare M J,Magliano D J,Zimmet P Z,et al.Glucose-Independent Ethnic Differences in Hb A1c in People Without Known Diabetes[J].Diabetes Care,2013,36(6):1534-1540.
  • 10Morris D H,Khunti K,Achana F,et al.Progression rates from Hb A1c 6.0 to 6.4%and other prediabetes definitions to type 2 diabetes:a meta-analysis.[J].Diabetologia,2013,56(7):1489-1493.

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