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布托啡诺预处理对依托咪酯全麻诱导时诱发肌阵挛的影响 被引量:8

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摘要 目的 观察布托啡诺预处理对依托咪酯全麻诱导时诱发肌阵挛的影响.方法 将100例ASA Ⅰ~Ⅱ级患者随机分为B组和S组各50例,分别给予布托啡诺0.015 mg/kg和等量生理盐水;给药2 min后,给予依托咪酯0.3 mg/kg开始麻醉诱导.依托咪酯给药2 min后,观察患者肌阵挛发生情况.结果 B组发生肌阵挛8例(16.0%),其中轻度4例、中度3例、重度1例;对照组发生肌痉挛37例(74.0%),其中轻度7例、中度11例、重度19例;两组肌阵挛发生率比较,P<0.01.S组中男性患者肌阵挛发生率为80.7%、女性为75.0%,P>0.05;20~35岁肌阵挛发生率为72.7%、36~ 50岁为82.3%、51 ~65岁为72.7%,P>0.05.结论 依托咪酯全麻诱导前2 min静脉给予布托啡诺可有效抑制依托咪酯诱发的肌阵挛.
出处 《山东医药》 CAS 2013年第48期58-60,共3页 Shandong Medical Journal
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