摘要
目的探讨最大b值对透明细胞癌多b值的DWI分析的影响。方法通过回顾性分析17例透明细胞癌患者的影像学资料,分别测量多b值(0 s/m m2~1200s/mm2)DWI图像中透明细胞癌的信号强度,采用双指数函数分析数据,根据最大b值(b max)的选择分为两组:组1(b max=800 s/mm2)和组2(b max=1200s/mm2)。分析两组的参数F、Dfast和Dslow有无差异,组间比较采用配对秩和检验(Wilcoxon)。结果透明细胞癌的DWI信号随着b值的增大而减小。双指数函数分析的参数F、Dfast和Dslow的中位数(及75%区间)在组1中分别依次为60.79%(37.79%,89.54%)、3.485×10-3mm2/s(2.028×10-3mm2/s,7.053×10-3mm2/s)和0.5837×10-3mm2/s(0mm2/s,1.161×10-3mm2/s);在组2中分别依次为77.84%(60.13%,89.06%)、2.918×10-3mm2/s(2.309×10-3mm2/s,5.749×10-3mm2/s)和0.1507×10-3mm2/s(0mm2/s,0.6583×10-3mm2/s)。各参数在两组间均无统计学差异(P>0.05)。结论在透明细胞癌的多b值DWI分析中,最大b值为800s/mm2和1200s/mm2对多b值DWI的分析结果没有明显的影响。
Objective To probe the influence ot maximal b values on the analyses of multi- b DWI used in clear cell renal carcinoma （CCRCC）. Material andMethods The imag- ing data, of 17 case with CCRCC confirmed bV pathologv after surgery, was analyzed retrospectively. The signal of parenchvma in C（2R.CC were measured on DWI with multi- b values （0 s/ram~ 1200 s/nun2） respectively, and the data was postprocessed using the bioexponential function with the maximal b （b）=800 s/nnll2 （Group 1） and 1200 s/mm2 （Group 2）, respectively. The parametm~, including F, Dfast and Dslow was assessed by paired Wilcoxon test. Results The si^znal of CCP, CC decreased with increased b factors. After the analyses of bioexponential function with different b, the medians （and interquartile range） of F, Dfast and Dslow are 60.79% （37.79%, 89.54%）, 3.485 ×10-3 mm2/s （2.1）28 ×10-2 mine/ s, 7.053 ×10^-3 mm2/s） and 0.5837 ×10-3mm2/s （0 mm-2/s, 1.161 ×10-3 mine/s） in Group 1, and 77.84% （60.13%, 89.（）6%）, 2.918 ×10 ^-3mm2/s （2.309 ×10-3 mm2/s, 5.749×10 ^-3 mine/s） and 0.1507 ×10＇3 mm-＇/s （0 mine/s, （I.6583 ×10 3 mnl_~/s） in Group 2, respectively. There arc no significant difference between two groups （P〉0.05）. Conclusion The differ- ence of two maximal b values, 800 s/mm2 and 1200 s/mm2, can＇ t affect the results in the postprocessing of nmlti-b DWI used in assessing CCRCC.
出处
《中国CT和MRI杂志》
2013年第6期79-81,94,共4页
Chinese Journal of CT and MRI
基金
常州市卫生局重大科技项目(编号:ZD201110)
常州市科技局重大项目(编号:CJ20122019)
关键词
透明细胞癌
磁共振
弥散成像
Clear cell renal cell carcinoma
Ma^metic resonance ima^in~
Diffusion weightedimaging
