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结肠癌转移相关基因1(MACC1)在肿瘤中的作用及其研究进展

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摘要 随着肿瘤靶向治疗研究的不断深入,肿瘤相关的分子标记也逐渐成为研究的前沿和热点。结肠癌转移相关基因1(metastasis-associated in colon cancer-1,MACC1)是对人类结肠癌组织、转移组织和正常组织进行全基因组扫描而发现的一个新基因。最近研究发现MACC1与其他肿瘤的发生发展关系也十分密切,可能成为肿瘤治疗的新的分子靶点。为了对MACC1的功能有一个全面的认识和了解,在本综述中,我们分析了MACC1的结构、MACC1与肿瘤发生发展之间的关系、MACC1与肿瘤转移之间的关系以及其在调控信号途径中的作用。
出处 《中国卫生产业》 2013年第33期21-22,24,共3页 China Health Industry
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参考文献7

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