摘要
目的 探讨急性脑卒中合并脑卒中相关性肺炎（SAP）患者的病原菌分布特点及耐药性,为合理使用抗生素提供依据.方法 回顾性分析131例急性脑卒中合并SAP患者的痰培养及药敏结果.结果 共分离出病原菌148株,其中革兰阴性菌占66.22％（98/148）,主要为肺炎克雷伯杆菌、铜绿假单胞菌、大肠埃希菌、鲍曼不动杆菌、阴沟肠杆菌等;革兰阳性菌占26.35％（38/148）,以金黄色葡萄球菌最多见,其次为凝固酶阴性葡萄球菌和粪肠球菌;真菌占7.43％（12/148）,主要为白色假丝酵母菌.致病菌对常用抗菌药物都不同程度地产生了耐药性.结论 SAP的主要病原菌是革兰阴性菌,耐药率普遍较高,应根据病原学分析,合理应用抗生素.
Objective To analyze the pathogens distribution and drug resistance in acute stroke with stroke associated pneumonia （SAP） patients,and provide references for proper clinical application of antibiotics.Methods A retrospective investigation was performed to analyze the pathogens and the drug resistance of 131 acute stroke with SAP patients.Results Among 148 strains of isolated pathogens,the Gram-negative bacteria accounted for 66.22% （98/148）,including Klebsiella pneumoniae,Pseudomonas aeruginosa,Escherichia coli,Acinetobacter baumannii,Enterobacter cloacae and so on.Gram-positive bacteria accounted for 26.35% （38/148）.Staphylococcus aureus ranked the first,followed by Coagulase negative staphylococcus and Enterococcus faecalis.Fungi accounted for 7.43% （12/148）,mainly including Candida albicans.They had varying degrees of resistance to commonly used antibiotics.Conclusions Gram-negative bacteria are predominant in SAP.Drug resistance is very serious,and the antibiotics should be selected in clinic according to the result of drug susceptibility test.
出处
《中国医师进修杂志》
2013年第34期22-24,共3页
Chinese Journal of Postgraduates of Medicine
关键词
肺炎
脑卒中相关性
病原菌
耐药性
Pneumonia, stroke-associated
Pathogenic bacteria
Drug resistance
作者简介
Email ： lalilu@ 126.com
