摘要
目的:评价阿奇霉素和清开灵序贯疗法对小儿肺炎的疗效及安全性。方法:120例小儿肺炎患儿随机分为观察组和对照组组各60例,观察组采用阿奇霉素序贯给药,对照组清开灵序贯给药,对比两组的疗效、细菌清除率、不良反应发生率等。结果:观察组患儿的临床有效率、胸部影像吸收所占比例明显高于对照组(P<0.05)。观察组发热消失时间、咳嗽消失时间、音消失时间、疗程均较对照组明显缩短(P<0.05);观察组不良反应发生率与对照组相比无统计学差异(P>0.05)。两组共分离出62株病原菌,其中观察组分离出病原菌29株,对照组分离出病原菌33株;治疗后细菌培养结果显示,观察组细菌清除率明显高于对照组(P<0.05)。结论:阿奇霉素治疗小儿肺炎疗效确切,临床症状消失快,且不良反应发生率低,未见有肝肾功能损害,安全性好。
Objective：To evaluation the efficacy and safety of sequential therapy of azithromycin and Qingkailing in children with pneumonia.Methods：120 cases of children with pneumonia were randomly divided into the observation group and treatment group every 60 cases,the observation group was treated with Azithromycin Sequential therapy, the control group used Qingkailing sequential administration, comparison of curative effect,bacterial clearance rate, incidence rate of adverse reaction of two groups.Results：Efficiency, chest X-ray absorption ratio of observed group was higher than that of control group （P〈0.05）. The observation group the disappearance time of fever, cough disappeared time, rales disappearance time, period of treatment were significantly shorter than the control group （P〈0.05）.The observation group chest impact absorption ratio was higher than that of the control group （93.7%vs 83.1%）;the observation group the incidence of adverse reaction was 6.7%, compared with the control group of 15%, no significant difference （P〈0.05）.Conclusion：Azithromycin in the treatment of infantile pneumonia curative effect, low incidence of adverse reactions, and worthy of clinical application.
出处
《中国医药导刊》
2013年第11期1858-1859,共2页
Chinese Journal of Medicinal Guide
关键词
阿奇霉素
清开灵
序贯疗法
小儿肺炎
Azithromycin
Qingkailing
Sequential therapy
Infantile pneumonia
