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自噬在蛛网膜下腔出血后早期脑损伤中作用的研究进展 被引量：3

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摘要 近几年研究发现,蛛网膜下腔出血（SAH）后72 h内即出现的早期脑损伤（early brain injury,EBI）与SAH的不良预后密切相关,成为研究关注的热点.自噬（autophagy）很早就被发现存在于多种组织细胞中,参与降解和回收受损细胞器和大分子物质,出现于多种生理过程和疾病的病理过程中.Lee 等[1]研究发现,SAH后立即可检测到皮质内自噬活性的增强.但自噬在SAH后EBI中的作用及具体机制尚不明确.我们就自噬与EBI的关系综述如下.
作者 肖遥 徐善才 史怀璋
机构地区 哈尔滨医科大学第一附属医院神经外科
出处 《中国脑血管病杂志》 CAS 2013年第10期553-556,共4页 Chinese Journal of Cerebrovascular Diseases
关键词 自噬 蛛网膜下腔出血 早期脑损伤
分类号 R743.35 [医药卫生—神经病学与精神病学]
作者简介 通讯作者：史怀璋，Email：huaizhangshi@163．com
  • 相关文献

参考文献29

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共引文献24

同被引文献35

  • 1幸志强,丁春平,邱志宏,易祥武,刘芳.ET_A受体拮抗剂BQ123对心肌梗死局部心肌组织中ET-1和ET受体分布的影响[J].中华老年多器官疾病杂志,2005,4(3):204-207. 被引量：3
  • 2刘宏雅.依达拉奉治疗脑出血的疗效观察[J].中国实用神经疾病杂志,2008,11(2):119-120. 被引量：2
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引证文献3

二级引证文献9

中国脑血管病杂志
2013年 第10期

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