摘要
本试验旨在研究灌服N-氨甲酰谷氨酸（NCG）对7～21日龄哺乳仔猪生长及内源精氨酸合成代谢的影响。试验选取6窝体重相近（（2．036±0．181）kg）、母猪胎次相同的4日龄“杜X（长×大）”三元杂交哺乳仔猪30头。每窝挑选5头，随机分在5个组中（每组6头）。每天每千克体重分别灌服0、100、150、200和250mgNCG。结果：①与对照组相比，灌服100和150mg·kg-1 NCG显著提高了仔猪平均日增重（P〈O．05）。②灌服NCG显著提高了哺乳仔猪血清中精氨酸含量（P〈O．05），灌服150mg·kg-1 NCG组仔猪血清瓜氨酸含量显著高于其他各组（P〈0．05）。③灌服100、150和200mg·kg-1 NCG显著提高了仔猪十二指肠CPS-I的活性（P〈0．05）。④灌服150mg·kg-1 NCG组十二指肠CPS-I表达量显著升高（P〈0．05）；100和150mg·kg-1组仔猪空肠和回肠中CPS-I表达量显著升高（P〈0．05）。结果表明，NCG可以促进哺乳仔猪生长发育及内源精氨酸的合成。
This study was conducted to investigate the effects of oral administration of N car- bamoylglutamate on growth performance and the endogenous anabolism of arginine of suckling piglets from 7 to 21 days of age. The ＂Duroc X （Landrace）〈 Yorkshire）＂ crossbred suckling piglets （n=30, 4-day-old） from 6 litters（same parity, 5 suckling piglets per litter） with similar weight（（2. 036 ＋ 0. 181） kg） were randomly allocated to five treatments （six replicates each）, which were orally administrated at the dose of 0,100,150,200 and 250 mg kg-lBW d-1 NCG, respectivly. Result： （1）Oral administration of 100 and 150 mg kg-1 BW NCG significantly in creased the average daily gain of suckling piglets compared with the control piglets （P〈0.05）.（2） Oral administration of 150 mg kg-1BW NCG significantly increased the plasma citrulline content of suckling piglets compared with the other suckling piglets （P〈0.05）. （3）Oral administration of 100,150 and 200 mg kg-1 BW NCG significantly increased the activity of carhamoyl phosphate synthase-I in duodenal of suckling piglets （P〈0.05）. （4）Oral administration of 150 mg kg-1 BW NCG significantly increased the gene expression of carbamoyl phosphate synthase-I in duode-nal （P〈0.05） ; 100 and 150 mg kg-1 BW NCG significantly improved the gene expression of carbamoyl phosphate synthase-I（P〈0.05） in jejunum and ileum. These results indicated that N- carbamoylglutamate could improve the growth performance and the endogenous anabolism of ar- ginine of suckling piglets.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
2013年第11期1844-1850,共7页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
河北省重大技术创新项目(07221008Z)
河北省自然科学基金项目(C2009000588)
作者简介
曹洪战（1970-），男，河北枣强人，教授，博士后，主要从事养猪生产研究，E-mail：chz516@126．com
通信作者：芦春莲，教授，E～mail：13833038290@163．com
