摘要
目的探讨孕母产前应用盐酸氨溴索对新生儿呼吸窘迫综合征发病影响的时效关系。方法将540例有早产征象的孕母按不同孕龄分为A、B、C三组各180例：A组孕龄为28—31周；B组孕龄为32—34周；C组孕龄为大于或等于35周。其中各组再随机分为用药小组90例和对照小组90例。用药小组在常规治疗的同时应用盐酸氨溴索，而对照小组只给予常规的药物治疗，对比产后新生儿呼吸窘迫综合征的发病率。结果A组的用药小组新生儿呼吸窘迫综合征发生率为21．11％，A组的对照小组新生儿呼吸窘迫综合征发生率为42．22％，两者比较，x2值为9．27，差异有显著统计学意义（P〈0．01）；B组的用药小组新生儿呼吸窘迫综合征发生率为14．44％，B组的对照小组新生儿呼吸窘迫综合征发生率为28．89％，两者比较，X2值为5．53，差异有统计学意义（P〈0．05）；C组的用药小组新生儿呼吸窘迫综合征发生率为6．67％，C组的对照小组新生儿呼吸窘迫综合征发生率为12．22％，两者比较，x2值为1．62，差异无统计学意义（P〉0．05）。结论孕母28～31周是产前应用盐酸氨溴索防治新生儿呼吸窘迫综合征的最佳时机。
Objective To explore theeffect of application of Ambroxol Hydrochloride for pregnant women on the occrence of respiratory distress syndrome for newborn baby. Methods 540 pregnant mother with premature birth symptom were divided into three groups according to differentgestational age ,women who prgnant for 28 ～ 31 weeks were included in groupA, women whopregnant for 32 ～ 34 weeks were divided into groupB, the others were divided into groupC, and 180women in each group. And them groupA, B, C were divided into two groups seperatly, the two groups were characteristic as treatment and control group, 90women in each group. The treatment group received ambroxol hydrochloride based on the normal treatment, but the control group only received normal treatment. Compare the occurrence of breathing pressed syndromeof newborn baby. Results The incidenceof newborn baby breathing pressed syndromewere 21. 11% （treatment）and 42. 22% （control） in groupA. The difference between the two groups was statisticallysignificant （ P 〈 0. 01 ） ; and the incidence of breathing pressed syndrome for newborn baby were 14.44% （treatment） and 28.89% （control） in groupB; The difference between the two groups was statistically Significant （ P 〈 0. 05 ）. The incidence of breathing pressed syndrome for newborn baby were 6.67% （treatment） and 12.22% （control） in groupC; The difference between the two groups present no statistically Significant （P 〈 0. 05）. Conclusions Gestational age during 28 ～ 31 weeks is the bestperiod to preventthe newborn baby breathing oressedfrom occuring by usingambroxol hvdrechloride.
出处
《齐齐哈尔医学院学报》
2013年第19期2883-2885,共3页
Journal of Qiqihar Medical University
关键词
产前
盐酸氨溴索
新生儿
呼吸窘迫综合征
时效
Before Delivery
Ambroxol Hydrochloride
Newborn Baby
Breathing PressedSyndrome
Chronergy
