摘要
目的:在区分侧脑室标志点的基础上,测量青年人、中年人及老年人正常侧脑室前角部、体部、后角部体积、角度。方法:应用3.0T MRI对60例健康成人(按年龄分为青、中、老年组,每组各20例)行侧脑室轴位的T2-MR扫描,确定标志点后对侧脑室分割。测量青年组、中年组及老年组侧脑室体积、角度,所得数据采用单因素方差分析,并作三维重建。结果:受试者侧脑室分割各标志如胼胝体、透明隔、穹窿、尾状核头、膜络裂等均能清晰显示。老年组侧脑室前角部、体部、后角部及整体体积均大于青年组,差异有统计学意义(均P<0.05)。中年组总体积稍大于青年组,但仅前角部差异有统计学意义(P<0.05)。老年组与中年组比较,前角部及后角部体积、侧脑室左、右前角角度以及左、右侧颞角宽度的差异有统计学意义(P<0.01)。结论:根据侧脑室标志点的确认原则,提出的标志点为侧脑室形态体积、角度的标准化测量提供了基础,其测量正常值有助于疾病诊断或为发病机制的研究提供基础。
Objective：Based on identification of anatomic landmarks of lateral ventricles, the study aims to measure the volumes and angles of head, body and tail of lateral ventricles in young, middle-aged and old people. Methods：Sixty healthy adults （divided equally into young group,middle-aged group and the elderly group by age） were scanned with T2-MR to determine the anatomic landmarks of lateral ventricle. Then the volumes, angles and numbers of scanning layers were measured in the three groups. The data were analyzed by one-way ANOVA. A lateral ventricle model was three-dimensional reconstructed. Results：All of the anatomic landmarks of lateral ventricles in subjects were distinguished clearly,such as the corpus callosum, septum pellucidum,fornix,head of caudate nucleus and membrane network bifida. The differences of the bilateral anterior horn,body and posterior horn of lateral ventricle and overall volume between the young group and the elderly group were statistically significant（all P 〈 0.05）. The volumes of lateral ventricle between middle-aged group and the young group had no significant differences except the anterior horn of lateral ventricle （P 〈 0.05）. The differences of the bilateral anterior horn,posterior horn of lateral ventricle and overall volume,left and right angles of anterior horn and width of temporal horn of lateral ventricle between the middle-aged group and the elderly group were significant （all P 〈 0.05）. Conclusion：According to the principles to confirm the anatomic landmarks of the lateral ventricle,the study provides a standardized form for measurements of volume and angle of lateral ventricle, which may be helpful for the diagnosis and research of the pathogenesis.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2013年第10期1469-1473,共5页
Journal of Nanjing Medical University(Natural Sciences)
关键词
侧脑室
磁共振
体积
角度
lateral ventricles
MRI
volume
angle
