摘要
目的探讨血清降钙素原(procaleitonin,PCT)对新生儿细菌感染性疾病早期诊断的意义。方法回顾性分析新生儿科收治的61例患儿,按出院诊断分成感染组和非感染组,其中感染组有35例,非感染组有26例,人院当天应用抗生素治疗前采3 ml静脉血作PCT检测,用酶联荧光免疫技术测定其PCT值,以PCT≥0.5 ng/ml为阳性,对两组患儿降钙素原检测结果进行对比,用统计软件SPSS 19.0进行数据分析。结果 61例新生儿中,感染组的PCT阳性率为94.29%,非感染组的PCT阳性率为11.54%,差异有统计学意义(P<0.05)。结论 PCT对新生儿细菌感染性疾病诊断具有较高的敏感度,对新生儿细菌感染引起全身性感染性疾病早期诊断优势明显。
Objective To investigate the significance of serum procalcitonin（PCT） in the early diagnosis of neonatal bacteri-al infection. Methods A retrospective study on role of serum procalcitonin in the diagnosis of neonatal bacterial infection was carried out on 61 neonatus in the Department of Paediatrics. They were divided into infection group（35 cases） and non-infection group（26 cases） according to the discharge diagnoses. 3ml venous blood was prepared for PCT tests on the first day at the hospi-tal. The level of PCT was measured by enzyme-linked fluorescent immunoassay, PCT ≥ 0.5 ng/ml was as positive. The detection results were compared between the two groups. Data were statistically analyzed by using statistical software SPSS 19. Results The positive rate of PCT in the infection group was 94.29% ,and in the non-infection group was 11.54% ,there were statistically significant differences between two groups （ P 〈 0.005 ）. Conclusion PCT has a high sensitivity to exclude the neonatal bacterial infections. There was also an obvious advantage in early diagnosis of systemic infection caused by neonatal bacterial infections.
出处
《中华全科医学》
2013年第11期1690-1691,共2页
Chinese Journal of General Practice
关键词
降钙素原
细菌感染
早期诊断
新生儿
Procalcitonin
Bacterial infections
Early diagnosis
Newborn
作者简介
通讯作者：李娟，电子信箱：251349726@qq．com
