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血清降钙素原在诊断系统性红斑狼疮合并细菌感染中的价值 被引量:1

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摘要 目的探究血清降钙素原(PCT)水平在系统性红斑狼疮(SLE)活动与合并细菌感染中的鉴别诊断价值。方法收集中南大学湘雅医院64例SLE伴发热住院患者,其中SLE活动期患者44例,SLE合并细菌感染患者20例,另选取SLE稳定期不发热患者20例作为对照,同时检测血样本PCT值、C反应蛋白(CRP)值、血沉及白细胞计数。结果SLE合并细菌感染组血清PCT、CRP水平明显高于SLE活动组,差异有统计学意义,以血清PCT≥0.5 ng/ml为诊断细菌感染阳性阈值,PCT对SLE合并细菌感染的发热患者诊断敏感性和特异性分别为80.0%、81.8%,阳性预测值、阴性预测值分别为66.7%、90.0%。结论血清PCT水平的升高对SLE发热患者是否合并细菌感染具有良好特异性和敏感性,对感染的早期诊断具有较好的临床参考价值。
出处 《实用预防医学》 CAS 2013年第10期1252-1253,共2页 Practical Preventive Medicine
作者简介 通讯作者:丘世飚。
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