摘要
Bladder cancer （BC） is the second most common malignancy of the human genitourinary tract,and is characterized by a high recurrence rate and expensive treatment） There is still no ideal biomarker for diagnosing or monitoring human BC.In the present study,we used proteomics analysis,including two-dimensional fluorescence difference gel electrophoresis （2D DIGE） and matrix-assisted laser desorption ionization time of flight/time of flight mass spectrometry （MALDI-TOF/TOF MS）,to identify new potential protein markers of BC.
Bladder cancer （BC） is the second most common malignancy of the human genitourinary tract,and is characterized by a high recurrence rate and expensive treatment） There is still no ideal biomarker for diagnosing or monitoring human BC.In the present study,we used proteomics analysis,including two-dimensional fluorescence difference gel electrophoresis （2D DIGE） and matrix-assisted laser desorption ionization time of flight/time of flight mass spectrometry （MALDI-TOF/TOF MS）,to identify new potential protein markers of BC.
作者简介
Correspondence to： ZHENG Shu-sen, Key Lab of Combined Multi- organ Transplantation, Ministry of Public Health; Key Lab of Organ Transplantation; Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University CoUege of Medicine, Hangzhou, Zhejiang 310003, China （Tel： 86-571-87236601. Fax： 86- 571-87236884. Email： shusenzheng@zju.edu.cn）
