期刊文献+

125例新生儿高未结合胆红素血症的临床分析 被引量:1

Clinical analysis of 125 cases in neonatal unconjugated hyperbilirubinemia
在线阅读 下载PDF
导出
摘要 目的 进一步做好新生儿高未结合胆红素血症的防治.方法 对2012年1月~2013年5月住院的新生儿高未结合胆红素血症125例的治疗方法、效果和不良反应进行分析,采用配对t检验方法比较光疗前后血清总胆红素(STB)的变化.结果 所有患儿经治疗皮肤黄染均明显消退或消失.41例光疗12h、8例连续光疗24 h、63例2次光疗12h前后STB比较差异有统计学意义.光疗后出现惊跳增多5例(5/119),腹泻2例(2/119)、皮疹2例(2/119).结论 光疗为主的综合治疗是快速降低未结合胆红素的有效方法. Objective To further improve the prevention and treatment of neonatal unconjugated hyperbilirubinemia. Methods The method,effect and adverse effect of 125 cases with neonatal unconjugated hyperbilirubinemia in hospital from January 2012 to May 2013 were analyzed,and the difference of total serum bilirubin (STB)between before pho- totherapy and after phototherapy was compared using paired-samples t test.Results Yellowing of the skin were signifi- cantly subsided or disappeared after comprehensive treatment.There were significant difference about STB between be- fore and after phototherapy for 12 hours in 41 cases,for 24 hours in 8 cases,and for twice 12 hours in 63 cases.After phototherapy,there were 5 cases of increased startle(5/119),2 cases of diarrhea(2/119),2 cases of skin rash(2/119).Conclusion Comprehensive treatment of mainly phototherapy can rapidly and effectively decrease the value of unconjugat- ed bilirubin.
作者 陈风展
出处 《中国当代医药》 2013年第29期177-178,共2页 China Modern Medicine
关键词 新生儿 高未结合胆红素血症 光疗 综合治疗 Newborn Unconjugated hyperbilirubinemia Phototherapy Comprehensive treatment
  • 相关文献

参考文献8

二级参考文献25

  • 1高瑞洁,牛乐珍.四黄金栀汤联合西医综合治疗新生儿高胆红素血症临床研究[J].中国妇幼保健,2004,19(8):74-76. 被引量:3
  • 2薛辛东.儿科学[M].2版.北京:人民卫生出版社,2010:141.
  • 3金汉珍,黄德眠,官希吉.实用新生儿学[M].3版.北京:人民卫生出版社,2009:263,265-266.
  • 4张家骧,魏克伦,薛辛东.新生儿急救[M].第3版.北京:人民卫生出版社,2003:275.
  • 5金汉珍,黄德珉,官希吉.实用新生儿学,第2版.北京:人民卫生出版社,1999:215-216.
  • 6Watchko JF. Identification of neonates at risk for hazardous hyper bilirubinemia: emerging clinical insights [ J . Pediatr Clin North Am,2009,56(3) :671-687.
  • 7胡亚美;江载芳.实用儿科学[M]北京:人民卫生出版社,2009438.
  • 8胡亚美;江载芳.实用儿科学[M]北京:人民卫生出版社,2009441.
  • 9Kurt A,Aygun AD,Kurt AN. Use of phototherapy for neonatal hy-perbilirubinemia affects cytokine production and lymphocyte Subsets[J].Neonatology,2009,(03):262-266.
  • 10高平明,张水堂,麦智广,吴时光,蒙来成,彭晓霞.佛山市52所医院新生儿疾病谱调查[J].实用儿科临床杂志,2008,23(14):1080-1081. 被引量:7

共引文献423

同被引文献16

  • 1邵肖梅,叶鸿瑶,丘小汕.实用新生儿学[M].4版.北京:人民卫生出版社,2011:807-808.
  • 2Esfandiarpour B,Gbrahimi H,Karkan M F,et al.Neo- natal exchange transfusion for hyperbilirubinemia in Gui- Ian(the north province of Iran):a 3-year experience [J].Turk J Pediatr,2012,54(6):626-631.
  • 3Haung M J,Kua K E,Teng H C,et al.Risk factors for severe hyperbilirubinemia in neonates[J].Pediatr Res,2004,56(5):682-689.
  • 4Bhutani V K.Bilirubin neurotoxicity in preterm infants: risk and prevention[J].J Clin Neonato,2013,2(2):61-69.
  • 5Campistol J,Galvez H,Cazorla A G,et al.Neurological dysfunction induced by bilirrubin[J].Neurologla,2012,27(4):202-211.
  • 6Heydarian F,Majdi M.Severe neonatal hyperbilirubi- nemia;causes and contributing factors leading to ex- change transfusion at Ghaem Hospital in Mashhad[J]. Acta Med Iran,2010,48(6):399-402.
  • 7Ahlfors C E,Wennberg R P,Ostrow J D,ei al.Un- bound(free)bilirubin:improving the paradigm for eval- uating neonatal jaundice[J].Clin Chem,2009,55(7):1288-1299.
  • 8Campistol J,Galvez H,Cazorla A G,et al.Neurological dysfunction induced by bilirrubin[J].Neurologia,2012,27(4):202-211.
  • 9US.Preventive Services Task Force.Screening of Infants for Hyperbilirubinemia to Prevent Chronic Bilirubin En- cephalopathy:Recommendation Statement[J].Am Fam Physician,2010,82(4):408-410.
  • 10Vandborg P K,Hansen B M,Greisen G,et al.Follow- up of neonates with total serum bilirubin levels >25 mg/dl:a Danish population-based study[J].Pediat- rics,2012,130(1):61-66.

引证文献1

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部