摘要
目的研究欣普贝生用于足月妊娠胎膜早破引产的最佳时机。方法将122例孕龄>37周、宫颈Bishop评分<6分的胎膜早破产妇随机分为三组,A组40例,B组41例,C组41例,三组分别于破膜后6、12、24 h未临产时使用欣普贝生,比较三组临产时间、产程时间、剖宫产率及母婴结局。结果 A组总产程时间、子宫过度刺激、羊水粪染、胎儿窘迫、新生儿窒息发生率分别为(9.33±2.12)h、15.00%、5.00%、10.00%、2.50%,与B、C组比较差异无统计学意义(P>0.05);A组临产时间为(11.12±3.23)h,短于B、C组(P<0.05、P<0.01);A组剖宫产率及产褥感染发生率分别为7.50%、5.00%,低于B、C组(P<0.05)。结论胎膜早破产妇应用欣普贝生越早,待产时间越短,能有效降低剖宫产率及产褥感染率。
Objective To study the best timing of Dinoprostone application on inducing labor of premature rupture of the membrane in full-time pregnancy. Methods 122 cases of gestational age ~ 37 weeks, Bishop score 〈 6 points, premature rupture of membranes women were randomly divided into 3 groups, 40 cases in group A, 41 cases in group B, 41 cases in group C, they were given Dinoprostone respectively at 6, 12, 24 h after rupture of membranes and not in labor, the labor time, the rate of cesarean section, maternal and child outcomes of 3 groups were compared. Results The total process time, uterine over-stimulation, amniotic fluid, fetal distress, incidence of neonatal asphyxia of group A was （9.33±2.12） h, 15.00%, 5.00%, 10.00%, 2.50%, there were no significant differences compared with group B, C （P 〉 0.05）; labor time of group A was （11.12±3.23） h, which was shorter than that in group B, C （P 〈 0.05, P 〈 0.01）; cesare- an section rate and the incidence of puerperal infection of group A was 7.50%, 5.00%, which was less than that in group B, C （P 〈 0.05）. Conclusion For puerpera with premature rupture of the membrane, the earlier Dinoprostone is ap- plied, the shorter the delivery time is, and it can reduce the rate of cesarean section and puerperal infection effectively.
出处
《中国医药导报》
CAS
2013年第26期79-81,共3页
China Medical Herald
基金
浙江省衢州市科技计划项目(编号20121090)
关键词
足月妊娠
胎膜早破
欣普贝生
引产
时机
Full-term pregnancy
Premature rupture of membranes
Dinoprostone
Inducting labor
Timing
作者简介
余海云（1971.2-）,女,汉族,副主任医师;研究方向：妊娠期肝胆汁淤积症.
