摘要
目的 探讨脂肪肝高脂血症与胰岛素抵抗 (IR)的关系。方法 以健康查体者 818例作为研究对象 ,分析其影响脂肪肝及高脂血症发生的年龄性别因素。结果 脂肪肝患病率 18 3% ,男性高于女性 ,45岁以下组男女差异显著 (P <0 0 1) ,5 0岁以上组男女差异不显著。血脂 (血清胆固醇TC及甘油三酯TG) 5 0岁以下组男性高于女性 ,其中TG差异显著 (P <0 0 1) ;5 0～ 6 0岁组女性高于男性 ,尤其TC差异显著 (P <0 0 5 ) ;5 0～ 6 0岁女性组与 45岁以下女性组比 ,血TC及TG值均增高明显 (P <0 0 1) ;6 0岁以上组男女血脂无显著差异。结论 女性围绝经期存在明显高脂血症及高脂肪肝发生率 ,可能与雌激素水平下降产生IR有关。
Objective To study the relation between fatty liver,hyperlipidemia and the insulin resistance.Methods To take 818 healthy persons as the study objects and analyze the age and gender factors affecting the pathogenesis of fatty liver and hyperlipidemia.Results The morbidity rate of fatty liver was 18 3%,which was higher in male group than that in female group,but the difference between two groups under 45 was distinct(P<0 01)and not distinct over 50.The blood fat (cholesterol TC,triglyceride TG) in male group was higher than that in female group under 50, of which the difference of TG was distinct(P<0 01),while the blood fat in the female group was higher than that in male group from 50 to 60, and the difference of TC was also distinct(P<0 05).There was no distinct difference of blood fat both male and female over 60.Conclusion The distinct being of hyperlipidemia and high morbidity rate of fatty liver for the females in the period of menopause might be related to the engendering of IR due to the reduction of estrogen.
出处
《中国全科医学》
CAS
CSCD
2000年第5期355-356,共2页
Chinese General Practice
