摘要
目的探讨辅助应用右美托咪定对妇科腹腔镜手术患者的麻醉深度及苏醒质量的影响。方法将86例妇科腹腔镜手术患者随机分为2组,每组43例。2组均行静吸复合全身麻醉,采用相同的麻醉诱导。治疗组于术前10 min静脉泵注右美托咪定,对照组则静脉泵注生理盐水。比较2组患者入室时、切皮时、拔管时、离开麻醉恢复室(PACU)时的心率(HR)、舒张压(DBP)、收缩压(SBP)、脑电双频指数(BIS)的变化,苏醒时间、拔管时间及离开PACU时间,以及不良反应发生情况。结果观察组HR、DBP及SBP在各时间段无显著变化,而对照组切皮时和拔管时HR、DBP及SBP均显著高于入室时。观察组切皮时及拔管时HR、DBP、SBP及BIS水平显著低于对照组,且拔管时间亦显著短于对照组。观察组苏醒期躁动、术后疼痛发生率显著低于对照组。结论对于妇科腹腔镜手术麻醉患者,术前10 min辅助应用右美托咪定可在提供满意镇静作用的同时,使血流动力学指标更为稳定,并提高麻醉恢复的质量,降低苏醒期躁动及术后疼痛发生率,值得在临床推广应用。
Objective To explore the influences of dexmedetomidine on anesthesia depth and awakening quality in patients with gynecological laparoscopic operation.Methods Eighty-six patients with gynecological laparoscopic operation were divided into two groups randomly,with 43cases in each group.The patients in two groups both received combined general intravenous-inhalation anesthesia and the same anesthesia induction.The treatment group was given dexmedetomidine 10 mins before operation,while the control group was given normal saline.The heart rate （HR）,diastolic blood pressure （DBP）,systolic blood pressure （SBP） and bispectral index （BIS）when patients arrived at operation room,skin incision,extubation and leaving postanesthesia care unit （PACU）,awakening time,extubation time and leaving PACU time,and adverse reactions in the two groups were compared.Results The levels of HR,DBP and SBP in the treatment group at each time point had no significant difference,while the levels of HR,DBP and SBP in the control group when skin incision and extubation were obviously higher than that when patients arrived at operation room.The levels of HR,DBP,SBP and BIS during skin incision and extubation in the treatment group were obviously lower than that in the control group,and the extubation time was also shorter.The incidences of dysphoria in revival period and postoperative pain in the treatment group were obviously lower than that in the control group.Conclusion Except for providing satisfactory sedation for anaesthetic patients in gynecological laparoscopic surgery,the adjuvant application of dexmedetomidine 10 mins before surgery can also make haemodynamic indexes more stable,improve the quality of anesthesia recovery,decrease the dysphoria in revival period and incidence of postoperative pain,so it deserves to be popularized and applied in clinical practice.
出处
《实用临床医药杂志》
CAS
2013年第14期65-67,共3页
Journal of Clinical Medicine in Practice
基金
中国高校医学期刊临床专项资金(11321023)
关键词
右美托咪定
腹腔镜
妇科
麻醉深度
苏醒质量
dexmedetomidine
laparoscopy
gynecology
anesthesia depth
awakening quality
